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首页> 美国卫生研究院文献>Filaria Journal >Random Amplified Polymorphic DNA (RAPD) for differentiation between Thai and Myanmar strains of Wuchereria bancrofti
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Random Amplified Polymorphic DNA (RAPD) for differentiation between Thai and Myanmar strains of Wuchereria bancrofti

机译：随机扩增多态性DNA（RAPD）用于区分泰国和缅甸的Wuchereria bancrofti菌株

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BackgroundLymphatic filariasis (LF) is a mosquito-borne disease caused by mosquito-transmitted filarial nematodes, including Wuchereria bancrofti and Brugia malayi. The Lymphatic Filariasis Elimination Program in Thailand has reduced the prevalence of nocturnally subperiodic W. bancrofti (Thai strain), mainly transmitted by the Ochlerotatus (Aedes) niveus group in Thailand to 0.57/100,000 population. However, it is estimated that more than one million Myanmar migrants with high prevalence of bancroftian filariasis have settled in the large urban cities of Thailand. These infected migrants carry the nocturnally periodic W. bancrofti (Myanmar strain) which has Culex quinquefasciatus as the main mosquito vector. Although transmissions of the Myanmar strain of W. bancrofti by the Thai Cx. quinquefasciatus has never been reported, previous study showed that Cx. quinquefasciatus could nurture the Myanmar strain of W. bancrofti to the infective stage. Thus, the potential now exists for a re-emergence of bancroftian filariasis in Thailand. The present study was undertaken in an attempt to differentiate between the Thai and Myanmar strains of W. bancrofti.
机译：背景淋巴丝虫病（LF）是由蚊子传播的丝虫线虫（包括Wuchereria bancrofti和Brugia malayi）引起的由蚊子传播的疾病。泰国的淋巴丝虫病消除计划已将夜间亚周期W. bancrofti（泰国株）的流行率降低了，主要由泰国的Ochlerotatus（Aedes）niveus组传播至0.57 / 100,000人口。但是，据估计，超过一百万缅甸班氏丝虫病流行率很高的缅甸移民已定居在泰国的大城市中。这些被感染的移民携带夜间周期性的班氏W. bancrofti（缅甸毒株），其以库蚊（Culex quinquefasciatus）为主要蚊媒。尽管由泰国Cx传播了W. bancrofti的缅甸株。 quinquefasciatus从未被报道过，先前的研究表明Cx。 quinquefasciatus可以将缅甸W. bancrofti菌株培育到感染期。因此，现在存在在泰国重新出现班克罗夫特型丝虫病的潜力。进行本研究以试图区分泰国和缅甸W.bancrofti菌株。

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