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首页> 美国卫生研究院文献>Frontiers in Pharmacology >Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used
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Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

机译：山茱mas和山茱Off—两种传统药用植物的相似之处和区别

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Among 65 species belonging to the genus Cornus only two, Cornus mas L. and Cornus officinalis Sieb. et Zucc. (Cornaceae), have been traditionally used since ancient times. Cornus mas (cornelian cherry) is native to southern Europe and southwest Asia, whereas C. officinalis (Asiatic dogwood, cornel dogwood) is a deciduous tree distributed in eastern Asia, mainly in China, as well as Korea and Japan. Based on the different geographic distribution of the closely related species but clearly distinct taxa, the ethnopharmacological use of C. mas and C. officinalis seems to be independently originated. Many reports on the quality of C. mas fruits were performed due to their value as edible fruits, and few reports compared their physicochemical properties with other edible fruits. However, the detailed phytochemical profiles of C. mas and C. officinalis, in particular fruits, have never been compared. The aim of this review was highlighting the similarities and differences of phytochemicals found in fruits of C. mas and C. officinalis in relation to their biological effects as well as compare the therapeutic use of fruits from both traditional species. The fruits of C. mas and C. officinalis are characterized by the presence of secondary metabolites, in particular iridoids, anthocyanins, phenolic acids and flavonoids. However, much more not widely known iridoids, such as morroniside, as well as tannins were detected particularly in fruits of C. officinalis. The referred studies of biological activity of both species indicate their antidiabetic and hepatoprotective properties. Based on the available reports antihyperlipidemic and anticoagulant activity seems to be unique for extracts of C. mas fruits, whereas antiosteoporotic and immunomodulatory activities were assigned to preparations of C. officinalis fruits. In conclusion, the comparison of phytochemical composition of fruits from both species revealed a wide range of similarities as well as some constituents unique for cornelian cherry or Asiatic dogwood. Thus, these phytochemicals are considered the important factor determining the biological activity and justifying the use of C. mas and C. officinalis in the traditional European and Asiatic medicine.
机译：在属于山茱us属的65个物种中，山茱Cornmas L.和山茱offsieb只有两个。 et Zucc。 （玉米科），自古以来就已被传统地使用。山茱（山茱cherry）原产于欧洲南部和西南亚，而山茱。（亚洲山茱wood，山茱dog）是一种落叶乔木，分布于东亚，主要分布于中国，韩国和日本。基于密切相关物种的不同地理分布，但明显不同的分类单元，C。mas和C. officinalis的民族药理学用途似乎是独立产生的。由于C. mas果实具有食用价值，因此进行了许多报道，很少有报道将其理化特性与其他食用果实进行比较。但是，从未比较过C. mas和C. officinalis，特别是水果的详细植物化学特征。这篇综述的目的是强调在假丝酵母和山茱C果实中发现的植物化学物质在生物学效果方面的异同，并比较两种传统物种的水果在治疗上的用途。 C. mas和C. officinalis的果实的特征在于存在次级代谢产物，特别是虹彩化合物，花青素，酚酸和类黄酮。但是，尤其是在C. officinalis的果实中，发现了更广为人知的鸢尾类化合物，如morroniside和单宁。对这两种物种的生物学活性的参考研究表明它们具有抗糖尿病和保肝作用。根据现有的报道，高脂血症和抗凝血活性似乎对于玛氏梭状芽孢杆菌果实的提取物是独特的，而抗骨质疏松和免疫调节活性被分配给 C的制剂。厚朴的水果。总之，对两个物种的果实的植物化学组成进行比较后发现，它们具有广泛的相似性，并且具有山茱cherry或亚洲山茱wood特有的某些成分。因此，这些植物化学物质被认为是决定生物活性和证明使用C的重要因素。 mas 和 C。在欧洲和亚洲的传统医学中

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