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Anthropometric and Health-Related Behavioral Factors in the Explanation of Social Inequalities in Low Birth Weight in Children with Prenatal Alcohol Exposure

机译:人体学和健康相关的行为因素解释了产前酒精暴露儿童低出生体重中的社会不平等

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摘要

There is evidence for social inequalities in the health status of children with prenatal alcohol exposure (PAE). This study aimed to describe social inequalities in low birth weight (LBW) in children/adolescents with PAE and to examine the contribution of anthropometric and health-related behavioral factors to the explanation of social inequalities. A total of 2,159 participants with parental self-reported moderate to regular PAE (enrolled in the cross-sectional German Health Interview and Examination Survey for Children and Adolescents) were examined. At similar levels of PAE, the risk of LBW was significantly increased in subjects with a low socioeconomic status (SES) (adjusted odds ratio (OR) 2.78, 95% confidence interval (CI) 1.59, 4.86) and middle SES (adjusted OR 2.04, 95% CI 1.28, 3.24). Maternal height, maternal body mass index (BMI) and smoking during pregnancy mediated the association. The mediating effect of maternal height was 12.5% to 33.7%. Maternal BMI explained 7.9% of the socioeconomic difference in LBW between the high and low SES groups in children with PAE. The mediating effect of smoking during pregnancy was 17.3% to 31.5%. Maternal height, maternal BMI and smoking during pregnancy together explained 24.4% to 60.1% of the socioeconomic differences in LBW in children with PAE. A large proportion of the socioeconomic differences in LBW in children with PAE can be attributed to anthropometric and health-related behavioral factors.
机译:有证据表明,产前饮酒(PAE)儿童的健康状况存在社会不平等现象。这项研究旨在描述患有PAE的儿童/青少年低出生体重(LBW)的社会不平等现象,并探讨人体测量学和健康相关行为因素对社会不平等现象的解释的贡献。共有2159名家长自我报告为中度至常规PAE的参与者(参加了横断面的德国儿童和青少年健康访谈和检查调查)。在类似的PAE水平下,低社会经济地位(SES)(调整后的优势比(OR)为2.78、95%置信区间(CI)为1.59、4.86)和中度SES(调整后的OR为2.04)的受试者中LBW风险显着增加,95%CI 1.28,3.24)。孕产妇身高,孕产妇体重指数(BMI)和怀孕期间的吸烟介导了这种关系。产妇身高的调节作用为12.5%至33.7%。母体BMI解释了PAE儿童中高和低SES组之间LBW的社会经济差异的7.9%。怀孕期间吸烟的中介作用为17.3%至31.5%。孕产妇身高,孕产妇体重指数和怀孕期间吸烟共同解释了PAE儿童LBW的社会经济差异的24.4%至60.1%。 PAE患儿LBW的社会经济差异很大一部分可归因于人体测量和健康相关的行为因素。

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