首页> 美国卫生研究院文献>Journal of Anatomy and Physiology >Histological and immunohistological investigation of alimentary tract lymphoid tissue in the koala (Phascolarctos cinereus) brushtail possum (Trichosurus vulpecula) and ringtail possum (Pseudocheirus peregrinus).
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Histological and immunohistological investigation of alimentary tract lymphoid tissue in the koala (Phascolarctos cinereus) brushtail possum (Trichosurus vulpecula) and ringtail possum (Pseudocheirus peregrinus).

机译:考拉(Phascolarctos cinereus)刷尾负鼠(Trichosurus vulpecula)和环尾负鼠(Pseudocheirus peregrinus)消化道淋巴样组织的组织学和免疫组织学研究。

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摘要

The histological appearance and distribution of T cells, B cells and plasma cells were investigated for oropharyngeal tonsils, small intestinal lymphoid aggregations (Peyer's patches), caecocolic lymphoid patches and mesenteric lymph nodes of koalas (Phascolarctos cinereus), common brushtail possums (Trichosurus vulpecula) and common ringtail possums (Pseudocheirus peregrinus). The histological organisation and distribution of lymphoid cell subpopulations of these tissues were similar to those described in eutherian mammals, although some differences were found in comparison with previous descriptions of American opossum tissues. The main variation among the 3 species was in the structural organisations of the oropharyngeal tonsil and the caecocolic lymphoid patch which were more complex in the koala than in possums. In the koala the extensive crypts of the oropharyngeal tonsils and folding of the mucosa of the caecocolic lymphoid patch increased their surface area and, in addition, both structures had areas of epithelium heavily infiltrated with T and B cells. These features could indicate that these structures are important in immunological surveillance of orally presented antigens in koalas.
机译:研究了口咽扁桃体,小肠淋巴样聚集(Peyer's斑块),盲肠淋巴样斑块和考拉(Phascolarctos cinereus),普通带尾pos(Trichosurus vulpecula)的T细胞,B细胞和浆细胞的组织学外观和分布。和普通的环尾负鼠(Pseudocheirus peregrinus)。这些组织的淋巴样细胞亚群的组织学组织和分布与在以太哺乳动物中描述的相似,尽管与美国负鼠组织的先前描述相比发现了一些差异。这3个物种之间的主要差异在于口咽扁桃体和盲肠淋巴样斑块的结构组织,它们在考拉中比在负鼠中更为复杂。在考拉中,口咽扁桃体的广泛隐窝和盲肠淋巴样斑块的粘膜折叠增加了它们的表面积,此外,两个结构的上皮区域都大量浸入了T和B细胞。这些特征可能表明这些结构在对考拉中口服呈递抗原的免疫学监测中很重要。

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