首页> 美国卫生研究院文献>Journal of the Boston Society of Medical Sciences >Correlation of estrogen and progesterone receptors with histologic differentiation in endometrial adenocarcinoma.
【2h】

Correlation of estrogen and progesterone receptors with histologic differentiation in endometrial adenocarcinoma.

机译:子宫内膜腺癌中雌激素和孕激素受体与组织学分化的关系。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Endometrial carcinomas from 58 patients were graded histologically, and the histologic grade was compared with the estrogen and progesterone receptor content of the tumor tissues. Receptor content was determined by multiple concentration saturation analysis and sucrose density gradient analysis. A positive correlation was found between the presence of estrogen and progesterone receptors and the degree of tumor differentiation. The majority (85%) of well-differentiated lesions contained significant amounts of both steroid receptor proteins. In contrast, only 13% of the poorly differentiated lesions were characterized by the presence of detectable levels of both estrogen and progesterone receptor proteins. The relationship of receptor content and degree of differentiation to prognosis and potential for response to hormonal therapy is discussed.
机译:对58例子宫内膜癌进行组织学分级,并将组织学分级与肿瘤组织中的雌激素和孕激素受体含量进行比较。通过多重浓度饱和度分析和蔗糖密度梯度分析确定受体含量。发现雌激素和孕激素受体的存在与肿瘤分化程度之间呈正相关。高度分化的病变大多数(85%)含有大量的两种类固醇受体蛋白。相反,只有13%的低分化病变的特征是存在可检测水平的雌激素和孕激素受体蛋白。讨论了受体含量和分化程度与预后和激素治疗反应潜力之间的关系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号