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首页> 美国卫生研究院文献>The Journal of Neurology and Psychopathology >Pathological torsional eye deviation during voluntary saccades: a violation of Listings law.
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Pathological torsional eye deviation during voluntary saccades: a violation of Listings law.

机译：自愿性扫视过程中的病理性扭转眼偏斜：违反了清单法。

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摘要

BACKGROUND: Under normal conditions, there are no torsional eye movements during voluntary saccades when the head is stationary (Listing's law). METHODS AND RESULTS: Using dual search coils for three dimensional eye movement recordings, a patient is reported who had direction specific rapid deviations of torsional eye position (up to 10.5 degrees) during voluntary saccades followed by a slow exponential torsional drift after the end of the saccade ("blip") towards the initial torsional eye position. In the absence of spontaneous nystagmus, this transient torsion means a violation of Listing's law for voluntary saccades and was associated with a lesion involving the cerebellar vermis, its deep nuclei, and the dorsolateral medulla. Amplitudes of the blip were larger for ipsilesional (hypermetric) than contralesional (hypometric) horizontal saccades. For comparison transient torsion during and after saccades was also examined in six normal subjects. Using the same in vivo calibration, there were no blips larger than 1.2 degrees in any of them. CONCLUSION: Transient torsion with large amplitudes can be clinically seen on bedside examination and might thus be a new clinical sign in the diagnosis of saccadic disorders.
机译：背景：在正常情况下，当头部静止时，自愿扫视期间眼睛不会发生扭转运动（李斯特定律）。方法和结果：使用双搜索线圈进行三维眼动记录，据报道，一名患者在自愿扫视过程中出现了特定方向的眼扭位置快速偏离（最大10.5度），随后在眼球结束后出现了缓慢的指数扭移。向初始扭转眼位置扫视（“闪烁”）。在没有自发性眼球震颤的情况下，这种短暂的扭转意味着违反了自愿性扫视的李斯特法则，并与涉及小脑bell骨，其深核和背外侧延髓的病变有关。同侧（超测）的对角线幅度比对侧（超测）的对角线幅度大。为了比较，在六个正常受试者中还检查了扫视期间和之后的短暂扭转。使用相同的体内校准，任何一个都不存在大于1.2度的斑点。结论：床旁检查可在临床上看到大幅度的短暂性扭转，因此可能是诊断眼跳疾病的新临床标志。

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