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The effect of fatigue on abnormal vibration induced illusion of movement in idiopathic focal dystonia

机译:疲劳对特发性局灶性肌张力障碍异常振动诱发运动错觉的影响

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摘要

>Objective: To examine the effects of fatigue on VIIM in patients with idiopathic torticollis. >Methods: An illusionary sensation of arm extension was evoked by an 80 Hz transcutaneous vibratory stimulus applied to the biceps brachii tendon while the arm was restrained. Blindfolded patients attempted to copy the perceived movement of the vibrated arm with the opposite (tracking) arm and the change in elbow angle of the tracking arm was quantified over 45 seconds. The tasks were repeated following volitional fatigue of the vibrated arm. >Results: The subnormal perception of VIIM perceived by patients with torticollis, occurring bilaterally and remote from the location of dystonic symptoms, was corrected by fatigue of the vibrated arm compared with prefatigue values (mean (SEM): 19.04° (1.76)° v 24.25° (2.41°); p = 0.01, paired t test). >Conclusions: While a combination of central or peripheral factors may be involved in the correction of abnormal perception of the vibration induced illusion of movement in dystonia, subnormal elasticity of muscle spindles could be implicated in the impaired perception of vibration induced illusionary movement and may predispose an individual towards developing idiopathic focal dystonia.
机译:>目的:研究疲劳对特发性斜颈患者的VIIM的影响。 >方法:手臂受限时,在肱二头肌肌腱上施加80 Hz的经皮振动刺激,会引起手臂伸展的幻觉。被蒙住眼睛的患者试图复制振动的手臂与相对的(跟踪)手臂的运动,并在45秒内量化跟踪手臂的肘部角度的变化。振动手臂自愿疲劳后,重复执行这些任务。 >结果:通过对振动臂的疲劳与疲劳前的值进行比较,校正了斜颈患者双侧发生且远离肌张力障碍症状的地方对VIIM的不正常感知(平均值(SEM):19.04) °(1.76)°v 24.25°(2.41°); p = 0.01,成对t检验)。 >结论:虽然中央或外围因素的组合可能参与了对肌张力障碍中振动引起的运动错觉的异常知觉的矫正,但肌肉纺锤的弹性低于正常水平可能与振动知觉受损有关会导致幻觉运动,并可能使个体倾向于发展特发性局灶性肌张力障碍。

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