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首页> 美国卫生研究院文献>Lipids in Health and Disease >Increased EPA levels in serum phospholipids of humans after four weeks daily ingestion of one portion chicken fed linseed and rapeseed oil
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Increased EPA levels in serum phospholipids of humans after four weeks daily ingestion of one portion chicken fed linseed and rapeseed oil

机译：每天摄入四分之一亚麻籽和菜籽油的鸡肉，每天食用四周后，人的血清磷脂中的EPA水平升高

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Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans ingesting the chicken. Forty-six young healthy volunteers (age 20–29) were randomly allocated into two groups in a double-blind dietary intervention trial, involving ingestion of about 160 g chicken meat per day for 4 weeks. The ingested meat was either from chickens given a feed concentrate resembling the commercial chicken feed, containing 4% soybean oil (SO), or the meat was from chickens given a feed where the soybean oil had been replaced by 2% rapeseed oil plus 2% linseed oil (RLO).Serum total cholesterol, LDL and HDL cholesterol, triacylglycerols, serum phospholipid fatty acid concentration, blood pressure, body weight and C-reactive protein were determined at baseline and post-intervention. In subjects consuming chicken meat from the RLO group there was a significantly (p < 0.001) increased concentration of EPA in serum phospholipids, and a reduced ratio between AA and EPA. The participants that had a low% of EPA + DHA in serum phospholipids (less than 4.6%), all increased their% of EPA + DHA after the four week intervention period when consuming the RLO chicken. No significant response differences in cholesterol, triacylglycerol, C-reactive protein, body weight or blood pressure were observed between the groups. This trial demonstrates that a simple change in chicken feed can have beneficial effects on amount of EPA and the AA/EPA ratio in human serum phospholipids.
机译：由于食物中花生四烯酸（AA）和EPA的含量可能对人体健康有影响，因此我们调查了鸡饲料的微小变化是否会影响人类摄食鸡的血脂浓度。在一项双盲饮食干预试验中，四十六名年轻健康志愿者（年龄在20-29岁之间）被随机分为两组，其中涉及每天摄入约160 g鸡肉，持续4周。摄入的肉来自鸡肉，其饲料浓缩物类似于商业鸡饲料，含有4％的豆油（SO），或者来自鸡肉的饲料，其中大豆油已被2％菜籽油加2％的豆油替代。在基线和干预后测定血清总胆固醇，LDL和HDL胆固醇，三酰甘油，血清磷脂脂肪酸浓度，血压，体重和C反应蛋白。在食用来自RLO组的鸡肉的受试者中，血清磷脂中EPA的浓度显着提高（p <0.001），而AA和EPA之间的比例降低。参与者在食用RLO鸡四个星期的干预期后，血清磷脂中EPA + DHA的百分比较低（低于4.6％），都增加了EPA + DHA的百分比。两组之间在胆固醇，三酰甘油，C反应蛋白，体重或血压方面没有观察到明显的反应差异。该试验表明，鸡饲料的简单变化可对人血清磷脂中的EPA含量和AA / EPA比产生有益影响。

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