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Production of the Novel Two-Peptide Lantibiotic Lichenicidin by Bacillus licheniformis DSM 13

机译：地衣芽孢杆菌DSM 13生产新型的两肽羊毛硫抗生素地衣素

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BackgroundLantibiotics are small microbial peptide antibiotics that are characterized by the presence of the thioether amino acids lanthionine and methyllanthionine. Lantibiotics possess structural genes which encode inactive prepeptides. During maturation, the prepeptide undergoes posttranslational modifications including the introduction of rare amino acids as lanthionine and methyllanthione as well as the proteolytic removal of the leader. The structural gene (lanA) as well as the other genes which are involved in lantibiotic modification (lanM, lanB, lanC, lanP), regulation (lanR, lanK), export (lanT(P)) and immunity (lanEFG) are organized in biosynthetic gene clusters.

机译：背景技术抗生素是小型微生物肽抗生素，其特征在于存在硫醚氨基酸羊毛硫氨酸和甲基羊毛硫氨酸。羊毛硫抗生素具有编码失活的前肽的结构基因。在成熟过程中，前肽会进行翻译后修饰，包括引入稀有氨基酸，如羊毛硫氨酸和甲基羊毛硫酮，以及蛋白水解去除前导肽。结构基因（lanA）以及涉及羊毛硫抗生素修饰的其他基因（lanM，lanB，lanC，lanP），调节（lanR，lanK），出口（lanT（P））和免疫（lanEFG）生物合成基因簇。

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期刊名称 PLoS Clinical Trials
作者
Jasmin Dischinger; Michaele Josten; Christiane Szekat; Hans-Georg Sahl; Gabriele Bierbaum;
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年(卷),期 2009(4),8
年度 2009
页码 e6788
总页数 11
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专利

1. Isolation, Structure Elucidation, and Synergistic Antibacterial Activity of a Novel Two-Component Lantibiotic Lichenicidin from Bacillus licheniformis VK21 [J] . Zakhar O. Shenkarev Ekaterina I. Finkina Elina K. Nurmukhamedova Sergey V. Balandin Konstantin S. Mineev Kirill D. Nadezhdin Zoya A. Yakimenko Andrey A. Tagaev Yuri V. Temirov Alexander S. Arseniev and Tatiana V. Ovchinnikova Biochemistry . 2010,第30期

机译：地衣芽孢杆菌VK21的新型两组分羊毛硫抗生素地衣素的分离，结构解析和协同抗菌活性。
2. Isolation, Structure Elucidation, and Synergistic Antibacterial Activity of a NovelTwo-Component Lantibiotic Lichenicidin from Bacillus licheniformis VK2l [J] . Zakhar O. Shenkarev, Ekaterina I. Finkina, Elina K. Nurmukhamedova, Biochemistry . 2010,第30期

机译：地衣芽孢杆菌VK2l的新型双组分羊毛硫抗生素地衣素的分离，结构解析和协同抗菌活性。
3. Impact of Domestication in the Production of the Class II Lanthipeptide Lichenicidin by Bacillus licheniformis I89 [J] . Caetano Tania, Suessmuth Roderich D., Mendo Sonia Current Microbiology: An International Journal . 2015,第3期

机译：驯化对地衣芽孢杆菌I89生产II类脂肽类地衣素的影响
4. Effect of Process Parameters on the Production of Cyclodextrin Using Cyclodextrin Glucanotransferase From Bacillus licheniformis [C] . R. C. Man, S. Selvanathan, S. M. Shaarani, International Conference on Separation Technology . 2020

机译：工艺参数对使用环糊精葡聚糖转移酶从芽孢杆菌的环糊精生产的影响
5. Studies in the antimicrobial mechanism of the lantibiotics nisin and sublancin, and, A Bacillus subtilis 168 expression system that displays the lantibiotic antimicrobial peptide sublancin on the cell surface. [D] . Villaruz, Amer Emilio Cosca. 2002

机译：研究了羊毛硫抗生素乳酸链球菌素和潜蛋白的抗菌机制，以及枯草芽孢杆菌168表达系统，该表达系统在细胞表面显示羊毛硫抗生素抗菌肽潜蛋白。
6. Enzymatic Synthesis of Apigenin Glucosides by Glucosyltransferase (YjiC) from Bacillus licheniformis DSM 13 [O] . Rit Bahadur Gurung, Eun-Hee Kim, Tae-Jin Oh, 2013

机译：地衣芽孢杆菌DSM 13的葡萄糖基转移酶（YjiC）酶促合成芹菜素苷
7. Production of the Novel Two-Peptide Lantibiotic Lichenicidin by Bacillus licheniformis DSM 13 [O] . Dischinger, Jasmin, Josten, Michaele, Szekat, Christiane, 2009

机译：地衣芽孢杆菌DSM 13生产新型的两肽羊毛硫抗生素地衣素
8. Interactions of 'Bacillus licheniformis' ATCC 10716 and Normal Flora of Human Skin. [R] . Bibel, D. J., Smiljanic, R. J., Lovell, D. J. 1978

机译：'地衣芽孢杆菌'aTCC 10716与人体皮肤正常菌群的相互作用。

Production of the Novel Two-Peptide Lantibiotic Lichenicidin by Bacillus licheniformis DSM 13

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