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The Epidemiology of Hip and Major Osteoporotic Fractures in a Dutch Population of Community-Dwelling Elderly: Implications for the Dutch FRAX® Algorithm

机译:荷兰社区老年人的髋骨和主要骨质疏松性骨折的流行病学:对荷兰FRAX®算法的启示

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摘要

BackgroundIncidence rates of non-hip major osteoporotic fractures (MOF) remain poorly characterized in the Netherlands. The Dutch FRAX® algorithm, which predicts 10-year probabilities of hip fracture and MOF (first of hip, humerus, forearm, clinical vertebral), therefore incorporates imputed MOF rates. Swedish incidence rate ratios for hip fracture to MOF (Malmo 1987–1996) were used to perform this imputation. However, equality of these ratios between countries is uncertain and recent evidence is scarce. Aims were to estimate incidence rates of hip fracture and MOF and to compare observed MOF rates to those predicted by the imputation method for the Netherlands.
机译:背景在荷兰,非髋关节重大骨质疏松性骨折(MOF)的发病率仍然很差。因此,荷兰的FRAX®算法可预测10年髋部骨折和MOF(髋部,肱骨,前臂,临床椎骨先发)的概率,因此将估算的MOF率纳入计算。瑞典人将髋部骨折的发生率与MOF的比率(Malmo 1987–1996)用于估算。但是,各国之间这些比率的均等性尚不确定,并且最近的证据很少。目的是评估髋部骨折和MOF的发生率,并将观察到的MOF率与荷兰采用插补法预测的MOF率进行比较。

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