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The Efficacy and Safety of Miconazole Nitrate Mucoadhesive Tablets versus Itraconazole Capsules in the Treatment of Oral Candidiasis: An Open-Label, Randomized, Multicenter Trial

机译：硝酸咪康唑粘膜黏附片与伊曲康唑胶囊在口腔念珠菌病中的疗效和安全性：一项开放标签，随机，多中心试验

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BackgroundOral candidiasis (OC) is a common oral fungal infection. Recently, miconazole mucoadhesive tablets have been gaining attention for OC treatment. Despite trials in patients with human immunodeficiency virus and cancer, evidence of its application in the large-scale, general population with OC is lacking. This study aimed to evaluate the efficacy and safety of miconazole nitrate mucoadhesive tablets in comparison with itraconazole capsules for OC treatment.

机译：背景口腔念珠菌病（OC）是常见的口腔真菌感染。近来，咪康唑粘膜粘附片剂已引起OC治疗的注意。尽管在针对人类免疫缺陷病毒和癌症的患者中进行了试验，但仍缺乏在大规模，普通人群中使用OC的证据。这项研究旨在评估硝酸咪康唑粘膜粘膜片与伊曲康唑胶囊用于OC治疗的疗效和安全性。

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期刊名称 PLoS Clinical Trials
作者
Zhimin Yan; Xiaosong Liu; Yang Liu; Ying Han; Mei Lin; Wenmei Wang; Xiaobing Guan; Shengrong Zhu; Handong Zhang; Qintao Wang; Lihong Chou; Xinghao Zhu; Hong Hua;
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年(卷),期 2011(11),12
年度 2011
页码 e0167880
总页数 12
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1. Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in pati [J] . Bensadoun RJ, Daoud J, El-Gueddari B, Cancer: A Journal of the American Cancer Society . 2008,第1期

机译：咪康唑50 mg粘膜黏附颊片与咪康唑500 mg凝胶治疗口咽念珠菌病的疗效和安全性比较：一项前瞻性，随机，单盲，多中心，比较性，Ⅲ期临床试验
2. 5515 POSTER Comparison of the efficacy and safety of miconazole 50 mg mucoadhesive buccal tablets to those of miconazole 500 mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomised, single blind, multicenter, comparative, phase III trial in patients treated with radiotherapy for head and neck cancer [J] . R.-J.Bensadoun, P.Attali European Journal of Cancer Supplements . 2007,第4期

机译：5515 POSTER咪康唑50 mg粘膜黏附颊片与咪康唑500 mg凝胶在口咽念珠菌病中的疗效和安全性比较：一项前瞻性，随机，单盲，多中心，比较，III期临床试验，用于放射治疗的患者头颈癌
3. Randomized, comparative, double-blind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: study of miconazole Lauriad(R) efficacy and safety (SMiLES). [J] . Vazquez JA, Patton LL, Epstein JB, HIV clinical trials . 2010,第4期

机译：咪康唑颊片和克霉唑锭治疗口咽念珠菌病的随机，比较，双盲，双假人，多中心试验：咪康唑Lauriad（R）的功效和安全性（SMiLES）研究。
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7. The Efficacy and Safety of Miconazole Nitrate Mucoadhesive Tablets versus Itraconazole Capsules in the Treatment of Oral Candidiasis: An Open-Label, Randomized, Multicenter Trial. [O] . Zhimin Yan, Xiaosong Liu, Yang Liu, 2016

机译：硝酸咪康唑粘膜胶囊与伊曲康唑胶囊治疗口腔念珠菌病的疗效和安全性：开放标签，随机，多中心试验。

The Efficacy and Safety of Miconazole Nitrate Mucoadhesive Tablets versus Itraconazole Capsules in the Treatment of Oral Candidiasis: An Open-Label, Randomized, Multicenter Trial

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