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Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model

机译:骨水泥中裂纹的扩散受水泥线特性的影响:使用XFEM界面损伤模型进行的参数研究

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摘要

Bulk properties of cortical bone have been well characterized experimentally, and potent toughening mechanisms, e.g., crack deflections, have been identified at the microscale. However, it is currently difficult to experimentally measure local damage properties and isolate their effect on the tissue fracture resistance. Instead, computer models can be used to analyze the impact of local characteristics and structures, but material parameters required in computer models are not well established. The aim of this study was therefore to identify the material parameters that are important for crack propagation in cortical bone and to elucidate what parameters need to be better defined experimentally. A comprehensive material parameter study was performed using an XFEM interface damage model in 2D to simulate crack propagation around an osteon at the microscale. The importance of 14 factors (material parameters) on four different outcome criteria (maximum force, fracture energy, crack length and crack trajectory) was evaluated using ANOVA for three different osteon orientations. The results identified factors related to the cement line to influence the crack propagation, where the interface strength was important for the ability to deflect cracks. Crack deflection was also favored by low interface stiffness. However, the cement line properties are not well determined experimentally and need to be better characterized. The matrix and osteon stiffness had no or low impact on the crack pattern. Furthermore, the results illustrated how reduced matrix toughness promoted crack penetration of the cement line. This effect is highly relevant for the understanding of the influence of aging on crack propagation and fracture resistance in cortical bone.Electronic supplementary materialThe online version of this article (10.1007/s10237-019-01142-4) contains supplementary material, which is available to authorized users.
机译:实验已经很好地表征了皮质骨的整体性质,并且已经在微观尺度上确定了有效的增韧机制,例如裂纹挠度。然而,目前难以通过实验测量局部损伤特性并分离它们对组织断裂阻力的影响。取而代之的是,可以使用计算机模型来分析局部特征和结构的影响,但是尚未很好地确定计算机模型中所需的材料参数。因此,本研究的目的是确定对于骨皮质中裂纹扩展至关重要的材料参数,并阐明需要通过实验更好地定义哪些参数。使用XFEM界面损伤模型(二维)进行了全面的材料参数研究,以模拟裂纹在骨微尺度上在骨周围的传播。使用方差分析针对三种不同的骨方向,评估了14个因素(材料参数)对四种不同结果标准(最大力,断裂能,裂纹长度和裂纹轨迹)的重要性。结果确定了与水泥线有关的影响裂纹扩展的因素,其中界面强度对于偏转裂纹的能力很重要。较低的界面刚度也有利于裂纹挠曲。但是,水泥线的性能尚不能通过实验很好地确定,需要更好地表征。基质和骨的刚度对裂纹模式没有影响或影响很小。此外,结果表明降低的基体韧性如何促进了水泥生产线的裂缝渗透。此效果与了解老化对皮质骨的裂纹扩展和抗断裂性的影响高度相关。电子补充材料本文的在线版本(10.1007 / s10237-019-01142-4)包含补充材料,可用于授权用户。

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