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首页> 美国卫生研究院文献>Springer Open Choice >Associations between Oxytocin Receptor (OXTR) Genotype and Elementary School Children’s Likability Dis-likability and Friendship among Classroom Peers: A Longitudinal Study
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Associations between Oxytocin Receptor (OXTR) Genotype and Elementary School Children’s Likability Dis-likability and Friendship among Classroom Peers: A Longitudinal Study

机译：催产素受体（OXTR）基因型与小学生同龄人同龄人之间的喜好反感和友谊之间的关联：一项纵向研究

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摘要

The single nucleotide polymorphism rs53576 of the oxytocin receptor (OXTR) gene is involved in forming and maintaining relationships in various social contexts. However, this has not been studied in the childhood peer context. The present study followed 359 children (51.6% girls) from age 9 to 12 to explore associations between OXTR rs53576 genotype (i.e., AA, AG or GG genotype) and three indicators of children’s relationships with peers: likability and dis-likability among, and friendship with, classroom peers. Our results showed that OXTR rs53576 was associated with likability among boys, but not with dis-likability and friendship or among girls. Boys with an A and a G allele (i.e., AG genotype) became increasingly more liked by their peers across the four-year studied period than those with two A alleles or two G alleles (i.e., AA and GG genotype). This study indicates that OXTR rs53576 genotype might influence children’s peer relationships, particularly their likeability among peers. Associations between OXTR rs53576 and peer relationships may differ depending on children’s sex and the specific type of peer-relationship under scrutiny.
机译：催产素受体（OXTR）基因的单核苷酸多态性rs53576参与各种社会背景下的形成和维持关系。但是，这尚未在童年同龄人的背景下进行过研究。本研究追踪了9岁至12岁之间的359名儿童（占女孩的51.6％），以探索OXTR rs53576基因型（即AA，AG或GG基因型）与儿童与同伴关系的三个指标之间的关联：亲和力和不喜欢彼此，以及与同学之间的友谊。我们的结果表明，OXTR rs53576与男孩之间的喜好相关，但与男孩之间的不喜欢和友爱无关。在为期四年的研究期内，具有A和G等位基因（即AG基因型）的男孩比同伴具有两个A等位基因或两个G等位基因（即AA和GG基因型）的男孩越来越受到同龄人的喜欢。这项研究表明，OXTR rs53576基因型可能会影响儿童的同伴关系，尤其是他们在同伴之间的亲和力。 OXTR rs53576与同伴关系之间的关联可能会有所不同，具体取决于孩子的性别和接受审查的同伴关系的特定类型。

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