首页> 美国卫生研究院文献>Springer Open Choice >Comparison of quality of life between 2-year and 3-or-more-year administration of leuprorelin acetate every-3-months depot in combination with tamoxifen as adjuvant endocrine treatment in premenopausal patients with endocrine-responsive breast cancer: a randomized controlled trial
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Comparison of quality of life between 2-year and 3-or-more-year administration of leuprorelin acetate every-3-months depot in combination with tamoxifen as adjuvant endocrine treatment in premenopausal patients with endocrine-responsive breast cancer: a randomized controlled trial

机译:绝经前内分泌反应性乳腺癌患者每隔3个月每2个月和3年或更长时间服用醋酸亮丙瑞林联合他莫昔芬辅助内分泌治疗的生活质量比较:一项随机对照试验

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摘要

BackgroundWe conducted an open-label, randomized controlled trial evaluating the appropriate treatment duration of leuprorelin acetate 3-month depot, TAP-144-SR (3M), administered postsurgically every 3 months for 2 years versus 3 or more (up to 5) years, in combination with tamoxifen, for 5 years in premenopausal endocrine-responsive breast cancer patients and reported similar survival benefit in the two treatment groups. We hereby present patient-reported quality of life (QOL) data obtained from this trial.
机译:背景我们进行了一项开放标签,随机对照试验,评估醋酸亮丙瑞林3个月长的制剂TAP-144-SR(3M)的适当治疗持续时间,每3个月进行术后2年(3年或以上(最多5年))联合他莫昔芬治疗绝经前内分泌反应性乳腺癌患者已有5年,并且在两个治疗组中报告了相似的生存获益。我们在此提供从该试验获得的患者报告的生活质量(QOL)数据。

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