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Numerical simulations of magnetic resonance elastography using finite element analysis with a linear heterogeneous viscoelastic model

机译:磁共振弹性成像的有限元分析与线性非均质粘弹性模型的数值模拟

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摘要

AbstractMagnetic resonance elastography (MRE) is a technique to identify the viscoelastic moduli of biological tissues by solving the inverse problem from the displacement field of viscoelastic wave propagation in a tissue measured by MRI. Because finite element analysis (FEA) of MRE evaluates not only the viscoelastic model for a tissue but also the efficiency of the inversion algorithm, we developed FEA for MRE using commercial software called ANSYS, the Zener model for displacement field of a wave inside tissue, and an inversion algorithm called the modified integral method. The profile of the simulated displacement field by FEA agrees well with the experimental data measured by MRE for gel phantoms. Similarly, the value of storage modulus (i.e., stiffness) recovered using the modified integral method with the simulation data is consistent with the value given in FEA. Furthermore, applying the suggested FEA to a human liver demonstrates the effectiveness of the present simulation scheme.
机译:摘要磁共振弹性成像技术(MRE)是一种通过解决MRI测量的组织中粘弹性波传播位移场的反问题来识别生物组织粘弹性模量的技术。由于MRE的有限元分析(FEA)不仅评估了组织的粘弹性模型,而且还评估了反演算法的效率,因此我们使用称为ANSYS的商用软件(用于组织内部波的位移场的齐纳模型)开发了MRE的FEA,以及称为改进积分法的反演算法。 FEA模拟的位移场的轮廓与MRE测量的凝胶体模的实验数据非常吻合。类似地,使用改进的积分方法和模拟数据恢复的储能模量(即刚度)值与FEA中给出的值一致。此外,将建议的有限元分析应用于人的肝脏证明了本模拟方案的有效性。

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