• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Springer Open Choice >Inflammatory cytokine and acute phase protein concentrations in the peripheral blood and uterine washings of cows with subclinical endometritis in the late postpartum period
【2h】

Inflammatory cytokine and acute phase protein concentrations in the peripheral blood and uterine washings of cows with subclinical endometritis in the late postpartum period

机译：产后晚期患有亚临床子宫内膜炎的母牛外周血和子宫冲洗液中炎症细胞因子和急性期蛋白的浓度

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of the study was to evaluate the concentrations of proinflammatory cytokines: tumor necrosis factor (TNF-α) and interleukin-6 (IL-6), anti-inflammatory cytokine interleukin-10 (IL-10), and acute phase proteins (APPs)—haptoglobin (Hp) and serum amyloid A (SAA) in serum and uterine washings of cows with subclinical endometritis, and compare them to healthy animals. The study was performed on 24 cows on day 60 after delivery. The cows were divided into two groups based on the results of cytological tests: 12 cows with subclinical endometritis and 12 healthy cows. Experimental material consisted of blood serum and uterine washings. The levels of the following cytokines in the study material were determined with ELISA: TNF-α, IL-6, IL-10 and APPs - Hp and SAA. The results show that the levels of TNF-α (p < 0.01), IL-6, IL-10 as well as SAA and Hp were significantly higher in the serum of cows with subclinical endometritis compared to the controls (p < 0.001). Uterine washings had significantly higher levels of IL-6, IL-10, and Hp in the experimental cows compared to the controls (p < 0.001). The demonstrated differences in the concentration of cytokines and APP between cows with subclinical endometritis and healthy cows, in both the serum and uterine washings, may suggest the usefulness of these parameters in the diagnosis of subclinical endometritis in cows in the late postpartum period.
机译：该研究的目的是评估促炎细胞因子的浓度：肿瘤坏死因子（TNF-α）和白细胞介素6（IL-6），抗炎细胞因子白介素10（IL-10）和急性期蛋白（ APPs）—亚临床子宫内膜炎母牛的血清和子宫清洗液中的触珠蛋白（Hp）和血清淀粉样蛋白A（SAA），并将它们与健康动物进行比较。该研究在分娩后第60天对24头母牛进行。根据细胞学检查结果将母牛分为两组：12头患有亚临床子宫内膜炎的母牛和12头健康的母牛。实验材料包括血清和子宫冲洗液。用ELISA测定研究材料中以下细胞因子的水平：TNF-α，IL-6，IL-10和APPs-Hp和SAA。结果表明，亚临床子宫内膜炎母牛血清中的TNF-α（p <0.01），IL-6，IL-10以及SAA和Hp的水平明显高于对照组（p <0.001）。与对照组相比，实验母牛的子宫冲洗液具有更高的IL-6，IL-10和Hp水平（p <0.001）。在血清和子宫冲洗液中，亚临床子宫内膜炎的母牛与健康母牛之间细胞因子和APP浓度的差异已证实，这可能表明这些参数对于产后晚期母牛亚临床子宫内膜炎的诊断是有用的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号