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MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis

机译：患有4期神经母细胞瘤的患者的MIBG扫描显示两种转移模式一种与MYCN扩增有关而在MYCN扩增的肿瘤中与更好的预后相关

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摘要

PurposeThe aim of this study was to find clinically relevant MIBG-avid metastatic patterns in patients with newly diagnosed stage 4 neuroblastoma.

机译：目的本研究的目的是在新诊断为4期神经母细胞瘤的患者中发现与临床相关的MIBG-avid转移模式。

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期刊名称 Springer Open Choice
作者
Gitta Bleeker; Berthe L. van Eck-Smit; Koos H. Zwinderman; Rogier Versteeg; Max M. van Noesel; Boen L. Kam; Gertjan J. Kaspers; Annelies van Schie; Susan G. Kreissman; Gregory Yanik; Barbara Hero; Matthias Schmidt; Geneviève Laureys; Bieke Lambert; Ingrid Øra; Johannes H. Schulte; Huib N. Caron; Godelieve A. Tytgat;
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年(卷),期 -1(42),-1
年度 -1
页码 222–230
总页数 9
原文格式 PDF
正文语种
中图分类外科学;
关键词
Neuroblastoma MIBG scan Metastatic patterns Metastases Outcome;

机译：神经母细胞瘤;MIBG扫描;转移模式;转移;结果;

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专利

1. 11q23缺失在无MYCN基因扩增的骨髓转移神经母细胞瘤中预后不良 [J] . 岳志霞, 邢天禹, 高超, 癌症（英文版） . 2020,第003期
2. MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis [J] . Bleeker Gitta, van Eck-Smit Berthe L., Zwinderman Koos H., European Journal of Nuclear Medicine and Molecular Imaging . 2015,第2期

机译：患有4期神经母细胞瘤的患者的MIBG扫描显示出两种转移模式，一种与MYCN扩增相关，而在MYCN扩增的肿瘤中与更好的预后相关
3. MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis [J] . Gitta Bleeker, Berthe L. Eck-Smit, Koos H. Zwinderman, European Journal of Nuclear Medicine and Molecular Imaging . 2015,第2期

机译：患有4期神经母细胞瘤的患者的MIBG扫描显示出两种转移模式，一种与MYCN扩增相关，而在MYCN扩增的肿瘤中与更好的预后相关
4. Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma. [J] . Kaneko S, Ohira M, Nakamura Y, Journal of Cancer Research and Clinical Oncology . 2007,第3期

机译：DDX1和NAG基因扩增/过表达与MYCN扩增的神经母细胞瘤患者预后的关系。
5. Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma [O] . J Buechner, E Tømte, B H Haug, 2011

机译：抑制肿瘤的microRNA let-7和mir-101靶向原癌基因MYCN并抑制MYCN扩增的神经母细胞瘤中的细胞增殖
6. MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis [O] . Bleeker, Gitta, van Eck-Smit, Berthe L., Zwinderman, Koos H., 2015

机译：患有4期神经母细胞瘤的患者的MIBG扫描显示出两种转移模式，一种与MYCN扩增相关，而在MYCN扩增的肿瘤中与更好的预后相关

MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis

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