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Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: a case example of pancreatitis risk among ulcerative colitis patients using mesalazine

机译：药物流行病学研究在解决药物警戒性问题中的作用：使用美沙拉嗪的溃疡性结肠炎患者中胰腺炎风险的案例

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PurposeWell-designed pharmacoepidemiology studies address several limitations of postmarketing spontaneous reports in regard to signal evaluation. This study evaluated a signal of disproportionate reporting of acute pancreatitis cases observed in patients with ulcerative colitis (UC) treated with MMX Multi Matrix System® (MMX®) mesalazine and demonstrated how inherent limitations of postmarketing reports were overcome.

机译：目的精心设计的药物流行病学研究解决了上市后自发报告在信号评估方面的一些局限性。这项研究评估了在使用MMX Multi MatrixSystem®（MMX®）美沙拉嗪治疗的溃疡性结肠炎（UC）患者中观察到的急性胰腺炎病例报告不成比例的信号，并证明了如何克服上市后报告的固有局限性。

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期刊名称 Springer Open Choice
作者
Leo Russo; Gary Schneider; Margarita Hauser Gardiner; Stephan Lanes; Paul Streck; Susan Rosen;
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作者单位

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年(卷),期 -1(70),6
年度 -1
页码 709–717
总页数 9
原文格式 PDF
正文语种
中图分类外科学;
关键词
Pancreatitis Ulcerative colitis Mesalazine Pharmacoepidemiology Pharmacovigilance;

机译：胰腺炎;溃疡性结肠炎;美沙拉嗪;药物流行病学;药物警戒;

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专利

1. Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: A case example of pancreatitis risk among ulcerative colitis patients using mesalazine [J] . RussoL., SchneiderG., GardinerM.H., European journal of clinical pharmacology . 2014,第6期

机译：药物流行病学研究在解决药物警戒性问题中的作用：使用美沙拉嗪的溃疡性结肠炎患者中胰腺炎风险的案例
2. Adherence, risk factors of non-adherence and patient's preferred treatment strategy of mesalazine in ulcerative colitis: multicentric observational study [J] . Radan Keil, Martin Wasserbauer, Zdena Zadorova, Scandinavian journal of gastroenterology. . 2018,第1a6期

机译：溃疡性结肠炎中胚轴非依恋和患者优选治疗策略的依从性，危险因素：多中心观察研究
3. Adherence, risk factors of non-adherence and patient's preferred treatment strategy of mesalazine in ulcerative colitis: multicentric observational study [J] . Keil Radan, Wasserbauer Martin, Zadorova Zdena, Scandinavian journal of gastroenterology. . 2018,第4期

机译：溃疡性结肠炎中胚轴非依恋和患者优选治疗策略的依从性，危险因素：多中心观察研究
4. Clinical efficacy of Qingchang Yuyang decoction combined with mesalazine in the treatment of ulcerative colitis [C] . Song Jinxuan International Conference on Life Sciences, Medicine, and Health . 2018

机译：青昌余阳汤与甲状腺碱治疗溃疡性结肠炎的临床疗效
5. Quality of life of patients with mucosal ulcerative colitis following ileal pouch anal anastomosis surgery. [D] . Quinn Griffin, Mary Therese. 2001

机译：回肠袋肛门吻合手术后粘膜溃疡性结肠炎患者的生活质量。
6. Acute Pancreatitis due to pH-Dependent Mesalazine That Occurred in the Course of Ulcerative Colitis [O] . Yoshinori Arai, Seiji Arihiro, Daisuke Ide, 2011

机译：溃疡性结肠炎过程中发生的pH依赖性美沙拉嗪引起的急性胰腺炎
7. Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: a case example of pancreatitis risk among ulcerative colitis patients using mesalazine [O] . 2014

机译：药物流行病学研究在解决药物警戒性问题中的作用：使用美沙拉嗪的溃疡性结肠炎患者中胰腺炎风险的案例

Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: a case example of pancreatitis risk among ulcerative colitis patients using mesalazine

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