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Three-dimensional reconstruction of brain structures of the rodent Octodon degus: a brain atlas constructed by combining histological and magnetic resonance images

机译:啮齿动物Octodon degus脑结构的三维重建:结合组织学和磁共振图像构建的脑图集

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摘要

Degus (Octodon degus) are rodents that are becoming more widely used in the neuroscience field. Degus display several more complex behaviors than rats and mice, including complicated social behaviors, vocal communications, and tool usage with superb manual dexterity. However, relatively little information is known about the anatomy of degu brains. Therefore, for these complex behaviors to be correlated with specific brain regions, a contemporary atlas of the degu brain is required. This manuscript describes the construction of a three-dimensional (3D) volume rendered model of the degu brain that combines histological and magnetic resonance images. This atlas provides several advantages, including the ability to visualize the surface of the brain from any angle. The atlas also permits virtual cutting of brain sections in any plane and provides stereotaxic coordinates for all sections, to be beneficial for both experimental surgeries and radiological studies. The reconstructed 3D atlas is freely available online at: .Electronic supplementary materialThe online version of this article (doi:10.1007/s00221-013-3667-1) contains supplementary material, which is available to authorized users.
机译:德格斯(Octodon degus)是啮齿动物,在神经科学领域越来越广泛地使用。 Degus显示出比大鼠和小鼠更复杂的行为,包括复杂的社交行为,声音交流和出色的手动灵活性所使用的工具。但是,关于胶质脑解剖学的信息相对较少。因此,为了使这些复杂的行为与特定的大脑区域相关联,需要现代的Degu脑图集。该手稿描述了结合组织学和磁共振图像的Degu脑的三维(3D)体积渲染模型的构建。该图集提供了多个优势,包括从任何角度可视化大脑表面的能力。该图集还允许在任何平面上虚拟切割大脑切片,并为所有切片提供立体定位坐标,这对实验手术和放射学研究均有益。可以从以下网站免费在线获取重建的3D地图集:电子补充材料本文的在线版本(doi:10.1007 / s00221-013-3667-1)包含补充材料,授权用户可以使用。

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