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Effect of baclofen on morphine-induced conditioned place preference extinction and stress-induced reinstatement in chronically stressed mice

机译：巴氯芬对吗啡诱导的慢性应激小鼠条件性位置偏爱绝种和应激诱导的恢复的影响

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Rationale and ObjectiveA stress-induced increase in excitability can result from a reduction in inhibitory neurotransmission. Modulation of gamma-aminobutyric acid (GABA)ergic transmission is an effective treatment for drug seeking and relapse. This study investigated whether baclofen, a GABAB receptor agonist, had an impact on morphine-induced conditioned place preference (CPP), extinction, and stress-induced relapse in chronically stressed mice.

机译：基本原理和目标应激诱导的兴奋性增加可能是抑制性神经传递的减少引起的。调节γ-氨基丁酸（GABA）的能量传递是寻求药物和复发的有效方法。这项研究调查了巴氯芬（一种GABA B受体激动剂）是否对吗啡诱导的条件性位置偏爱（CPP），绝种和应激诱导的慢性复发小鼠产生影响。

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期刊名称 Springer Open Choice
作者
Shanshan Meng; Wuxing Quan; Xu Qi; Zhiqiang Su; Shanshan Yang;
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作者单位

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年(卷),期 -1(231),1
年度 -1
页码 27–36
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
关键词
Addiction Morphine Baclofen Restraint stress Forced swim stress Dose Schedule Conditioned place preference Reinstatement Extinction;

机译：成瘾;吗啡;巴氯芬;束缚压力;强迫游泳压力;剂量;时间表;有条件的地方偏爱;恢复;消光;

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专利

1. Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice [J] . MengS., QuanW., QiX., Psychopharmacology . 2014,第1期

机译：巴氯芬对吗啡诱导的慢性应激小鼠条件性位置偏爱，绝种和应激诱导的恢复的影响
2. Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement [J] . Hossein Khaleghzadeh-Ahangar, Abbas Haghparast Neurochemical research . 2017,第11期

机译：宫内大麻加毒剂激动剂减毒恢复但不会消灭吗啡诱导的条件偏好; 灭绝时期不同特点的证据和恢复
3. Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice [J] . Girardi Bruna A., Fabbrin Shaiana, Wendel Arithane L., Psychopharmacology . 2020,第3期

机译：氨基胺，NMDA受体的阳性调节剂，促进消失并防止恢复在小鼠中的吗啡诱导的条件偏好
4. Stress-induced birefringence and extinction ratio [C] . Gaoping Li, Beijing Institute of Technology, Xian, Automated Optical Inspection for Industry: Theory, Technology, and Applications II . 1998

机译：应力诱导的双折射和消光比
5. Chronic stress during adolescence alters alcohol-induced conditioned place preference in mice selectively bred for high alcohol preference but not low alcohol preference [D] . Breit, Kristen R. 2015

机译：青春期的慢性应激改变了酒精诱导的条件性位置偏爱，该小鼠是为高酒精偏爱而不是低酒精偏爱而选择性繁殖的
6. The Effect of High-Frequency Electrical Stimulation of Bilateral Nucleus Accumbens on the Behavior of Morphine-Induced Conditioned Place Preference Rats at Extinction and Reinstatement Phases [O] . Chunhui Yang, Yiqing Qiu, Xiaowu Hu, 2020

机译：双侧核毒刺伤对混合物诱导的条件偏好大鼠在消光和恢复相中的影响
7. Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice [O] . Shanshan Meng, Wuxing Quan, Xu Qi, 2013

机译：巴氯芬对吗啡诱导的慢性应激小鼠条件性位置偏爱，绝种和应激诱导的恢复的影响

Effect of baclofen on morphine-induced conditioned place preference extinction and stress-induced reinstatement in chronically stressed mice

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