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首页> 美国卫生研究院文献>Springer Open Choice >Obesity at age 20 and the risk of miscarriages irregular periods and reported problems of becoming pregnant: the Adventist Health Study-2
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Obesity at age 20 and the risk of miscarriages irregular periods and reported problems of becoming pregnant: the Adventist Health Study-2

机译：20岁肥胖症流产不规则时期和所报告的怀孕问题的风险：Adventist Health Study-2

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In a group of 46,000 North-American Adventist women aged 40 and above, we investigated the relationships between body mass index (BMI, kg/m2) at age 20 and the proportion of women who reported at least one miscarriage, periods with irregular menstruation or failing to become pregnant even if trying for more than one straight year. Approximately 31, 14 and 17 %, respectively, reported the three different problems related to reproduction. Positive age- and marital status adjusted relationships were found between BMI at age 20 and periods with irregular menstruation or failing to become pregnant even if trying for more than 1 year, but not with the risk of miscarriages. Women with BMI ≥ 32.5 kg/m2 when aged 20 had approximately 2.0 (95 % CI: 1.6, 2.4) and 1.5 (95 % CI: 1.3, 1.9) higher odds for irregular periods or failing to get pregnant, respectively, than women with BMI in the 20–24.9 kg/m2 bracket. These relationships were consistently found in a number of strata of the population, including the large proportion of the women who never had smoked or never used alcohol. Underweight (BMI < 18.5 kg/m2) when aged 20 marginally (approximately 15 %) increased the risk of failing to get pregnant within a year. Thus, obesity at age 20 increases the risk of reporting some specific reproductive problems, but not the risk of miscarriages.Electronic supplementary materialThe online version of this article (doi:10.1007/s10654-012-9749-8) contains supplementary material, which is available to authorized users.
机译：在一组46,000名40岁及以上的北美复临信徒妇女中，我们调查了20岁时的体重指数（BMI，kg / m 2 ）与报告至少一次流产，月经不调或即使连续一年以上都无法怀孕。分别约有31％，14％和17％报告了与生殖有关的三个不同问题。在20岁的BMI与月经不调或即使怀孕超过1年也未能怀孕的时期之间，发现了年龄和婚姻状况调整的正相关关系，即使尝试了一年以上，也没有流产的风险。在20岁时BMI≥32.5 kg / m 2 的女性在不规律时期或未能达到以下标准的几率高出约2.0（95％CI：1.6，2.4）和1.5（95％CI：1.3，1.9）分别比体重指数在20–24.9 kg / m 2 支架内的女性怀孕。在许多人口阶层中都发现了这些关系，其中包括从未吸烟或从未使用过酒精的很大比例的妇女。体重不足（BMI <18.5 kg / m 2 ）到20岁时（约15％）会增加一年内无法怀孕的风险。因此，在20岁时肥胖会增加报告某些特定生殖问题的风险，但不会增加流产的风险。电子补充材料本文的在线版本（doi：10.1007 / s10654-012-9749-8）包含补充材料，可供授权用户使用。

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