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The Global Landscape of Occupational Exposure Limits—Implementation of Harmonization Principles to Guide Limit Selection

机译:职业接触限值的全球概况—实施协调原则以指导限值的选择

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摘要

Occupational exposure limits (OELs) serve as health-based benchmarks against which measured or estimated workplace exposures can be compared. In the years since the introduction of OELs to public health practice, both developed and developing countries have established processes for deriving, setting, and using OELs to protect workers exposed to hazardous chemicals. These processes vary widely, however, and have thus resulted in a confusing international landscape for identifying and applying such limits in workplaces. The occupational hygienist will encounter significant overlap in coverage among organizations for many chemicals, while other important chemicals have OELs developed by few, if any, organizations. Where multiple organizations have published an OEL, the derived value often varies considerably—reflecting differences in both risk policy and risk assessment methodology as well as access to available pertinent data. This article explores the underlying reasons for variability in OELs, and recommends the harmonization of risk-based methods used by OEL-deriving organizations. A framework is also proposed for the identification and systematic evaluation of OEL resources, which occupational hygienists can use to support risk characterization and risk management decisions in situations where multiple potentially relevant OELs exist.
机译:职业接触限值(OELs)是基于健康的基准,可以将测量或估计的工作场所接触与之进行比较。自从将OELs引入公共卫生实践以来,多年来,发达国家和发展中国家都建立了衍生,设定和使用OELs的程序,以保护接触危险化学品的工人。但是,这些过程千差万别,因此导致在确定和应用工作场所此类限制方面产生了混乱的国际格局。职业卫生学家将在许多化学品的组织间覆盖范围严重重叠,而其他重要化学品具有很少(如果有)组织开发的OEL。在多个组织发布了OEL的情况下,得出的值通常会相差很大-反映了风险政策和风险评估方法以及对可用相关数据的访问方面的差异。本文探讨了OEL差异的根本原因,并建议统一OEL派生组织使用的基于风险的方法。还提出了一个用于识别和系统评估OEL资源的框架,在存在多个潜在相关OEL的情况下,职业卫生学家可以使用该框架来支持风险特征描述和风险管理决策。

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