Hydrophilicity and Cell Affinity of Atmospheric-Pressure Plasma Jet-Treated Nerve Regeneration Conduit

Lin Lou; Jia Zhou; Nanliang Chen

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Hydrophilicity and Cell Affinity of Atmospheric-Pressure Plasma Jet-Treated Nerve Regeneration Conduit

机译：大气压等离子体喷射治疗神经再生导管的亲水性和细胞亲和力

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Nerve conduits made of biodegradable materials will become important in repairing nerve injuries. To improve hydrophilicity and cell affinity of braided, biodegradable, peripheral-nerve regeneration conduits and to promote regeneration of an injured nerve, a poly(glycolide-co-L-lactide) (PGLA) nerve regeneration conduit was treated with an atmospheric-pressure plasma jet (APPJ). Surface modification of the material was achieved. Using a wicking property survey, X-ray photoelectron spectroscopic (XPS) analysis, in vitro cell culture experiments, methylthiazolyl tetrazolium (MTT) cell proliferation assays, and field emission scanning electron microscopic (FESEM) analysis, the influence of APPJ treatment on hydrophilicity and cell affinity of three different nerve regeneration conduits was determined.

机译：由可生物降解材料制成的神经导管在修复神经损伤中将变得重要。为了提高编织的，可生物降解的周围神经再生导管的亲水性和细胞亲和力，并促进受伤神经的再生，用大气压等离子体处理了聚乙交酯-丙交酯（PGLA）神经再生导管。喷射（APPJ）。实现了材料的表面改性。使用芯吸特性调查，X射线光电子能谱（XPS）分析，体外细胞培养实验，甲基噻唑基四唑（MTT）细胞增殖测定和场发射扫描电子显微镜（FESEM）分析，APPJ处理对亲水性和确定了三种不同神经再生导管的细胞亲和力。

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来源
《AATCC review》 |2009年第6期|38-42|共5页
作者
Lin Lou; Jia Zhou; Nanliang Chen;
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作者单位

Zhejiang Sci-Tech University & Donghua University;

Zhejiang Provincial People's Hospital & Shanghai Jiao Tong University Affiliated First People's Hospital;

Donghua University;

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原文格式 PDF
正文语种 eng
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关键词
APPJ; biodegradation; braiding; cell affinity; hydrophilicity; nerve regeneration conduit; PGLA; plasma;

机译：APPJ;生物降解编织细胞亲和力亲水性神经再生导管PGLA;等离子体;

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专利

1. Nanofibrous Nerve Conduits with Nerve Growth Factors and Bone Marrow Stromal Cells Pre-Cultured in Bioreactors for Peripheral Nerve Regeneration [J] . Zhou Gan, Chang Wei, Zhou Xiaqing, ACS applied materials & interfaces . 2020,第14期

机译：纳米纤维神经管道，具有神经生长因子和骨髓基质细胞预培养的生物反应器，用于外周神经再生
2. Nerve regeneration across a 2-cm gap in the rat median nerve using a resorbable nerve conduit filled with Schwann cells. [J] . Sinis N, Schaller HE, Schulte Eversum C, Journal of neurosurgery. . 2005,第6期

机译：使用充满雪旺细胞的可吸收神经导管，在大鼠正中神经的2厘米间隙处进行神经再生。
3. Sciatic nerve regeneration by cocultured schwann cells and stem cells on microporous nerve conduits [J] . DaiL.-G., HuangG.-S., HsuS.-H. Cell transplantation . 2013,第11期

机译：通过在微孔神经导管上共培养雪旺细胞和干细胞来坐骨神经再生
4. Drug Loaded, Biodegradable Nerve Conduits for the SimultaneousChemical and Electrical Stimulation of Neural Cells as a TherapeuticApproach for Peripheral Nerve Regeneration [C] . Franziska Schmidt, Zahra Ghalanbor, Frank Thormann, International Conference on Processing and Manufacturing of Advanced Materials . 2009

机译：药物负载，可生物降解的神经管道，用于术语和电气刺激神经细胞作为外周神经再生的疗效
5. Incorporation of guidance cues in novel nerve guidance conduits for peripheral nerve regeneration of large defects. [D] . Shah, Munish B. 2016

机译：在新的神经引导导管中引入引导线索，以使大缺陷的周围神经再生。
6. Effects of nerve cells and adhesion molecules on nerve conduit for peripheral nerve regeneration [O] . Joo-Ryun Chung, Jong-Won Choi, Joseph P. Fiorellini, 2017

机译：神经细胞和黏附分子对周围神经再生的神经导管的影响
7. Additive Manufacturing of Nerve Decellularized Extracellular Matrix-Contained Polyurethane Conduits for Peripheral Nerve Regeneration [O] . Yi-Wen Chen, Chien-Chang Chen, Hooi Yee Ng, 2019

机译：神经脱细胞外细胞外基质的添加剂制造包含用于周围神经再生的聚氨酯导管
8. Enhancing Peripheral Nerve Regeneration with a Novel Drug Delivering Nerve Conduit. [R] . Shea, J., Agarwal, J. 2017

机译：用新型药物提供神经导管增强周围神经再生。

Hydrophilicity and Cell Affinity of Atmospheric-Pressure Plasma Jet-Treated Nerve Regeneration Conduit

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