B9-serine residue is crucial for insulin actions in glucose metabolism

Liao Zhi-Yong; Tang Yue-Hua; Xu Ming-Hua

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B9-serine residue is crucial for insulin actions in glucose metabolism

机译：B9-丝氨酸残基对葡萄糖代谢中胰岛素的作用至关重要

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Compar- ed with native insulin, the receptor binding activity of E, D-insulin was 31/100; the stimulating activity of E,D- Insulin in glucose transport and lipogenesis were 45/100 And 40/100 respectively; the stimulations of Glut4 Translocation and insulin receptor autophosphorylation of E,D-insulin were about 58/100 and 46/100 respectively. B9-serine residue is crucial for insulin Actions in glucose metabolism.

机译：与天然胰岛素相比，E，D-胰岛素的受体结合活性为31/100；与天然胰岛素相比，E，D-胰岛素的结合活性为31/100。 E，D-胰岛素对葡萄糖转运和脂肪生成的刺激活性分别为45/100和40/100。 E，D-胰岛素的Glut4易位和胰岛素受体自身磷酸化的刺激分别约为58/100和46/100。 B9丝氨酸残基对于胰岛素在葡萄糖代谢中的作用至关重要。

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《Acta Pharmacologica Sinica》 |2001年第10期|p.939-943|共5页
作者
Liao Zhi-Yong; Tang Yue-Hua; Xu Ming-Hua;
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正文语种 eng
中图分类药理学;
关键词
insulin; adipocytes; monosaccharide transport proteins;

机译：胰岛素;脂肪细胞单糖转运蛋白;

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B9-serine residue is crucial for insulin actions in glucose metabolism

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