Effect of endothelin-1 injected into rostral ventrolatral medulla on cardiovascular responses in cats

Yang Xin-Liang; Fu Wei-Jun; Hou Gnag-Xing

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Effect of endothelin-1 injected into rostral ventrolatral medulla on cardiovascular responses in cats

机译：腹侧腹侧延髓注射内皮素-1对猫心血管反应的影响

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AIM: To study the effect of endotherlin-1 (ET-1) in the rostral ventrolateral medulla (rVLM) on cardiovascular responses in cats. METHODS: The stereotatic technique and microinjection method were used. RESULTS: ET-1 (4 μmol·L~-1 0.5 μL) microinjected into rVLM induced mean arterial pressure (MAP) increasing (3.7±1.3) beats·min~-1, and renal nerve activity (RNA) intensifying 45 /100 ± 10 /100. CONCLUSION: ET-1 microinjected into rVLM could involve with Control regulation of cardiovascular and sympathetic Nerve activity.

机译：目的：探讨内皮素-1（ET-1）在猫腹侧延髓（rVLM）对心血管反应的影响。方法：采用立体定向技术和显微注射方法。结果：ET-1（4μmol·L〜-1 0.5μL）微注射入rVLM引起的平均动脉压（MAP）增加（3.7±1.3）次·min〜-1，肾神经活性（RNA）增强45/100 ±10/100。结论：rVLM微注射ET-1可能参与了心血管和交感神经活动的调控。

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来源
《Acta Pharmacologica Sinica》 |1999年第6期|p.566-570|共5页
作者
Yang Xin-Liang; Fu Wei-Jun; Hou Gnag-Xing;
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正文语种 eng
中图分类药理学;
关键词
endothelin-1; heart rate; blood pressure;

机译：内皮素-1;心率;血压;

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1. The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats. [J] . Wu WC, Wang Y, Su CK, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2001,第2a3期

机译：nNOS / cGMP信号转导系统参与了由猫的前额腹外侧延髓中NMDA受体的激活所诱导的心血管反应。
2. Cardiovascular and sympathetic effects of L-glutamate and glycine injected into the rostral ventrolateral medulla of conscious rats. [J] . Sakima A, Yamazato M, Sesoko S, Hypertension research: Official journal of the Japanese Society of Hypertension . 2000,第6期

机译：L-谷氨酸和甘氨酸注射入意识大鼠的前额腹外侧延髓的心血管和交感作用。
3. Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat. [J] . Chan JY, Chan SH, Chang AY Neuropharmacology . 2004,第8期

机译：延髓腹侧延髓中NOS亚型对与大鼠甲胺磷中毒相关的心血管反应的不同贡献。
4. Neuroprotective Role of Coenzyme Q10 against Dysfunction of Mitochondrial Respiratory Chain at Rostral Ventrolateral Medulla during Fatal Mevinphos Intoxication in the Rat [C] . F C.H. LI, H P TSENG, A Y.W. CHANG Asian Society for Mitochondrial Research and Medicine . 2005

机译：辅酶Q10对大鼠致致哺乳期髓质髓质髓质髓质髓质髓质髓质髓质髓质中的功能障碍的神经保护作用
5. Trigeminal-rostral ventromedial medulla involvement in contralateral deep tissue orofacial hyperalgesia. [D] . Chai, Bryan Y. 2013

机译：三叉神经-腹侧腹膜延髓累及对侧深部组织或面神经痛。
6. Cardiovascular responses produced by resistin injected into paraventricular nucleus mediated by the glutamatergic and CRFergic transmissions within rostral ventrolateral medulla [O] . Abolfazl Akbari, Gholamali Jelodar 2020

机译：抵抗素注射到脑室腹外侧延髓内的谷氨酸能和CRF能传递介导的室旁核中产生的心血管反应
7. Cardiovascular responses to injections of angiotensin II or carbachol into the rostral ventrolateral medulla in rats with AV3V lesions [O] . Vieira Alexandre Antonio, Colombari Eduardo, De Luca Laurival A., 2013

机译：患有AV3V病变的大鼠对前额腹外侧延髓注射血管紧张素II或卡巴胆碱的心血管反应

Effect of endothelin-1 injected into rostral ventrolatral medulla on cardiovascular responses in cats

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