Effect of moxonidine on carotid sinus baroreflex in anesthetized rats

Xu Yan-Fang; He Rui-Rong

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Effect of moxonidine on carotid sinus baroreflex in anesthetized rats

机译：莫索尼定对麻醉大鼠颈动脉窦压力感受性反射的影响

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AIM: To study the effect of moxonidine (Mox) on carotid sinus baroreflex. METHODS: By perfusing the carotid sinus in anesthetized rats, the functional parameters of baroreflex were measured. The femoral artery was perfused with constant flow and the change of perfusing pressure was recorded to determine the effect of Mox on vascular tone. CONCLUSION: Mox inhibits carotid Baroreflex via its constrictive action on sinus wall.

机译：目的：研究莫索尼定（Mox）对颈窦窦压力反射的作用。方法：通过在麻醉的大鼠中灌注颈动脉窦，测量压力反射的功能参数。用恒定流量灌注股动脉并记录灌注压力的变化，以确定Mox对血管张力的影响。结论：Mox通过对窦壁的收缩作用抑制颈动脉Baroreflex。

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《Acta Pharmacologica Sinica》 |1999年第7期|p.604-608|共5页
作者
Xu Yan-Fang; He Rui-Rong;
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正文语种 eng
中图分类药理学;
关键词
moxonidine; carotid sinus; baroreflex;

机译：莫索尼定颈动脉窦压力反射;

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Effect of moxonidine on carotid sinus baroreflex in anesthetized rats

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