Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs

Xie Qiang-Min; Zeng Ling-Hui; Zheng Yi-Xiong

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Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs

机译：班布特罗对豚鼠支气管收缩的支气管扩张作用

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AIM: To study the effects of bambuterol (Bam) on bronchoconstriction in guinea pigs. METHODS: bronchosphasm induced by histamine aerosol, lung resistance (R_L) and dynamic lung compliance (C_dyn) changes induced by ovalbumin aerosol in vivo, isolated resting lung parenchyma strips, and carbamylcholine- induced tracheal constriction in vitro in guinea pig were investigated. CONCLUSION: Bam showed a long-acting bron- Chodilation by its slow metabolism in vivo.

机译：目的：研究班布特罗（Bam）对豚鼠支气管收缩的影响。方法：研究了由组胺气雾剂引起的支气管痉挛，卵清蛋白气雾剂在体内引起的肺抵抗力（R_L）和动态肺顺应性（C_dyn）变化，分离的静息肺实质条带以及氨甲酰胆碱在豚鼠体内引起的气管收缩。结论：Bam在体内具有缓慢的代谢，显示出长效的bron- Chodilation。

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来源
《Acta Pharmacologica Sinica》 |1999年第7期|p.651-654|共4页
作者
Xie Qiang-Min; Zeng Ling-Hui; Zheng Yi-Xiong;
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正文语种 eng
中图分类药理学;
关键词
bronchodilator agents; terbutaline; histamine;

机译：支气管扩张剂;特布他林组胺;

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1. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. [J] . Hori M, Iwama T, Asakura Y, European Journal of Pharmacology: An International Journal . 2009,第1a3期

机译：NT-702（盐酸帕格瑞利，NM-702）是一种新型有效的磷酸二酯酶3抑制剂，可抑制豚鼠的哮喘反应，同时具有支气管扩张作用和抗炎作用。
2. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. [J] . Hori M, Iwama T, Asakura Y, European Journal of Pharmacology: An International Journal . 2009,第1a3期

机译：NT-702（盐酸普罗利氏菌，NM-702），新颖和有效的磷酸二酯酶3抑制剂，抑制了豚鼠的哮喘反应，具有支气管扩张和抗炎作用。
3. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. [J] . Hori M, Iwama T, Asakura Y, European Journal of Pharmacology: An International Journal . 2009,第1a3期

机译：NT-702（盐酸普罗利氏菌，NM-702），新颖和有效的磷酸二酯酶3抑制剂，抑制了豚鼠的哮喘反应，具有支气管扩张和抗炎作用。
4. Comparison of voltage-sensitive dye di-4-ANNEPS effects in isolated hearts of rat, guinea pig, and rabbit [C] . Fialova K., Kolarova J., Provaznik I., 2010 Computers in Cardiology . 2010

机译：电压敏感染料di-4-ANNEPS在大鼠，豚鼠和兔离体心脏中的作用比较
5. Effects of dietary cholesterol and carbohydrate restriction on plasma and hepatic lipid metabolism, atherosclerosis and inflammation in guinea pigs [D] . Torres-Gonzalez, Moises 2007

机译：饮食中胆固醇和碳水化合物的限制对豚鼠血浆和肝脂质代谢，动脉粥样硬化和炎症的影响
6. The effects of a novel sulphidopeptide leukotriene antagonist BAY x7195 against elicited bronchoconstriction in the anaesthetized guinea-pig [O] . H P Francis, U P Patel, A M Thompson, 1998

机译：新型硫肽白三烯拮抗剂BAY x7195对麻醉的豚鼠引起的支气管收缩的影响
7. Tracheal Relaxing Effects and β2-Selectivity of TA-2005, a Newly Developed Bronchodilating Agent, in Isolated Guinea Pig Tissues [O] . Hideo Kikkawa, Kazuaki Naito, Katsuo Ikezawa 1991

机译：在分离的豚鼠组织中，TA-2005的气管放松效果和β2选择性，新开发的支气管扩张剂，豚鼠组织
8. TERTIARY BLAST EFFECTS: THE EFFECTS OF IMPACT ON MICE, RATS, GUINEA PIGS AND RABBITS. Technical Progress Report [R] . 1961

机译：第三次爆发效应：影响对小鼠，大鼠，豚鼠和家兔的影响。技术进步报告

Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs

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