Inhibitory effects of estradiol on inward rectifier and delayed rectifier K~+ currents in guinea pig ventricular myocytes

Zhang Yi; Song Li-Lin; Gu Shuang-Zhen

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Inhibitory effects of estradiol on inward rectifier and delayed rectifier K~+ currents in guinea pig ventricular myocytes

机译：雌二醇对豚鼠心室肌细胞内向整流子和延迟整流子K〜+电流的抑制作用

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AIM: To study the effects of estradiol (Est) on inward rectifier K~+ (I_KI) and delayed rectifier K~+ (I_K) channels in isolated guinea pig ventricular myocytes. MEHTODS: Using whole cell patch-clamp recording Tehcniques. CONCLUSION: Est possessed blocking effects on both I_KI and I_K channels in guinea pig ventricular myocytes.

机译：目的：研究雌二醇（Est）对豚鼠心室肌细胞内向整流子K〜+（I_KI）和延迟整流子K〜+（I_K）通道的影响。方法：使用全细胞膜片钳记录Tehcniques。结论：Est对豚鼠心室肌细胞的I_KI和I_K通道均具有阻断作用。

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《Acta Pharmacologica Sinica》 |1999年第7期|p.631-634|共4页
作者
Zhang Yi; Song Li-Lin; Gu Shuang-Zhen;
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正文语种 eng
中图分类药理学;
关键词
estradiol; patch-clamp techniques; myocardium;

机译：雌二醇膜片钳技术;心肌层;

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2. Inhibitory Effects of Glycyrrhetinic Acid on the Delayed Rectifier Potassium Current in Guinea Pig Ventricular Myocytes and HERG Channel [J] . Delin Wu, Linqing Jiang, Hongjin Wu, Evidence-based complementary and alternative medicine: eCAM . 2013,第16期

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4. Electrophysiological Effects of SN-6, a Novel Na~+/Ca~(2+) Exchange Inhibitor on Membrane Currents in Guinea Pig Ventricular Myocytes [C] . CHUN-FENG NIU, YASUHIDE WATANABE, TAKAHIRO IWAMOTO, International Conference on Na/Ca Exchange . 2007

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7. Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes [O] . Bosch, RF, Gaspo, R, Busch, AE, 1998

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8. Studies on Lymphokines: The Production of Antibody to Guinea Pig Lymphotoxin and its use to Distinguish Lymphotoxin from Migration Inhibitory Factor and Mitogenic Factor. [R] . Gately, M. K., Gately, C. L., Henney, C. S., 1975

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Inhibitory effects of estradiol on inward rectifier and delayed rectifier K~+ currents in guinea pig ventricular myocytes

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