Hypotensive effect of tenuifolic saponin and its mechanism

Peng Wen-Duo

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Hypotensive effect of tenuifolic saponin and its mechanism

机译：替诺福利皂苷的降压作用及其机制

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AIM: To study the effect of tenuifolic saponin (TS) on arterial pressure. METHODS: Mean arterial pressure (MAP) was recorded from left carotid artery in rat which was anesthetized with urethane and then injected iv gtt with a transfusion of NaCl 0.15 mol· L~-1. Systolic blood pressure (SBP) of conscious rat And renovascular hypertensive rat (RVHR) was Measured by tail cuff method. CONCLUSION: TS reduced the arterial pressure, not Related to vagus excitation, ganglionic blockade, and Peripheral α-adrenergic-, M-cholinergic-, and H_1- Receptors.

机译：目的：研究替诺福利皂苷（TS）对动脉压的影响。方法：记录大鼠左颈动脉的平均动脉压（MAP），用氨基甲酸乙酯麻醉，然后静脉输注0.15mol·L〜-1的NaCl静脉注射。用尾套法测量清醒大鼠和肾血管性高血压大鼠的收缩压（SBP）。结论：TS降低了动脉压，与迷走神经兴奋，神经节阻滞和周围的α-肾上腺素能受体，M-胆碱能受体和H_1受体无关。

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《Acta Pharmacologica Sinica》 |1999年第7期|p.639-642|共4页
作者
Peng Wen-Duo;
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正文语种 eng
中图分类药理学;
关键词
tenuifolic saponin; blood pressure; renovascular hypertension;

机译：Tenuifolic皂苷;血压;肾血管性高血压;

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Hypotensive effect of tenuifolic saponin and its mechanism

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