Anti-inflammatory and nitric oxide-inhibiting properties of granulocyte colony-stimulating factor

Georg Hoffmann; Wolfgang Schobersberger

首页> 外文期刊>Acta Pharmacologica Sinica >Anti-inflammatory and nitric oxide-inhibiting properties of granulocyte colony-stimulating factor

【24h】

Anti-inflammatory and nitric oxide-inhibiting properties of granulocyte colony-stimulating factor

机译：粒细胞集落刺激因子的抗炎和一氧化氮抑制特性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A proposed scheme between the possible interactions of pro- and anti-inflammatory cytokines, NO and G-CSF during severe inflammation/infection is Presented. Taken together, these data indicate that G- CSF exhibits anti-inflammatory properties which may Prove to be beneficial in situations associated with an Increased activity of the cellular immune system. Since the suppressive effects of G-CSF on the Production of pro-inflammatory mediators like TNF-α And nitric oxide are most likely neither cell type nor Tissue specific, it is conceivable that NO release induced By pro-inflammatory mediators can be reduced by G- CSF in various organ systems and in different forms of Shock.

机译：提出了在严重炎症/感染过程中促炎和抗炎细胞因子，NO和G-CSF可能相互作用之间的拟议方案。综上所述，这些数据表明G-CSF表现出抗炎特性，在与细胞免疫系统活性增加相关的情况下可能被证明是有益的。由于G-CSF对促炎性介质如TNF-α和一氧化氮的产生的抑制作用很可能既不是细胞类型也不是组织特异性的，因此可以想象，促炎性介质诱导的NO释放可通过G减少-脑脊液在各种器官系统和不同形式的休克。

著录项

来源
《Acta Pharmacologica Sinica》 |1999年第8期|p.673-681|共9页
作者
Georg Hoffmann; Wolfgang Schobersberger;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
granulocyte colony-stimulating factor; cytokines; infection;

机译：粒细胞集落刺激因子;细胞因子感染;

相似文献

外文文献
中文文献
专利

1. A randomized trial comparing the combination of granulocyte-macrophage colony-stimulating factor plus granulocyte colony-stimulating factor versus granulocyte colony-stimulating factor for mobilization of dendritic cell subsets in hematopoietic proge [J] . Lonial S, Hicks M, Rosenthal H, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2004,第12期

机译：一项随机试验比较了粒细胞-巨噬细胞集落刺激因子与粒细胞集落刺激因子与粒细胞集落刺激因子的组合以动员造血过程中的树突状细胞亚群
2. Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor | Haematologica [J] . Ingmar Bruns, Ulrich Steidl, Johannes C. Fischer, Haematologica . 2008,第3期

机译：与未结合的粒细胞集落刺激因子相比，聚乙二醇化的粒细胞集落刺激因子可动员具有不同干和祖细胞亚群且具有不同功能特性的CD34 +细胞|血液学
3. Direct anti-inflammatory effects of granulocyte colony-stimulating factor (G-CSF) on activation and functional properties of human T cell subpopulations in vitro [J] . Malashchenko Vladimir Vladimirovich, Meniailo Maxsim Evgenievich, Shmarov Viacheslav Anatolievich, Cellular immunology . 2018,第期

机译：粒细胞菌落刺激因子（G-CSF）对体外人T细胞群激活和功能性的直接抗炎作用
4. Conjugation of High-Molecular Weight Poly(ethylene glycol) to Cytokines: Granulocyte-Macrophage Colony-Stimulating Factors as Model Substrates [C] . Merry R.Sherman, L.David Williams, Mark G.P.Saifer, Poly(ethylene glycol) : Chemistry and biological applications . 1997

机译：高分子量聚乙二醇与细胞因子的缀合：粒细胞-巨噬细胞集落刺激因子作为模型基质。
5. Characterization of granulocyte-macrophage colony-stimulating factor signaling in RUNX1-ETO leukemogenesis [D] . Weng, Stephanie. 2016

机译：Runx1-EtO白血病中粒细胞 - 巨噬细胞菌落刺激因子信号传导的表征
6. Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line. [O] . Ana Luísa Vital, Margarida Gonçalo, M Teresa Cruz, 2003

机译：地塞米松可防止皮肤树突状细胞系中粒细胞巨噬细胞集落刺激因子诱导的核因子-κB活化诱导型一氧化氮合酶表达和一氧化氮生成。
7. Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor [O] . Bruns, Ingmar, Department of Hematology, Oncology and Clinical Immunology, Steidl, Ulrich, 2008

机译：与未结合的粒细胞集落刺激因子相比，聚乙二醇化的粒细胞集落刺激因子可动员具有不同干和祖细胞亚群且具有不同功能特性的CD34 +细胞
8. Interdependence of the Radioprotective Effects of Human Recombinant Interleukin 1alpha, Tumor Necrosis Factor alpha, Granulocyte Colony-Stimulating Factor, and Murine Recombinant Granulocyte-Macrophage Colony-Stimulating Factor [R] . Neta, R., Oppenheim, J. J., Douches, S. D. 1988

机译：人重组白细胞介素1α，肿瘤坏死因子α，粒细胞集落刺激因子和小鼠重组粒细胞 - 巨噬细胞集落刺激因子的辐射保护作用的相互依赖性

Anti-inflammatory and nitric oxide-inhibiting properties of granulocyte colony-stimulating factor

摘要

著录项

相似文献

相关主题

期刊订阅