Intrathecal injection of corticotropin inhibited nitric-oxide synthase-positive neuron increase in rat spinal cord after formalin-induced hyperalgesia

Zhou Hong-Jie; Li Hai-Di; Li Xi-Cheng

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Intrathecal injection of corticotropin inhibited nitric-oxide synthase-positive neuron increase in rat spinal cord after formalin-induced hyperalgesia

机译：鞘内注射促肾上腺皮质激素抑制福尔马林引起的痛觉过敏后大鼠脊髓中一氧化氮合酶阳性神经元的增加

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AIM: To study the effects of corticotropin (Cor) on formalin-inducd hyperalgesia and the change of nitric- oxide synthase (NOS)-positive neurons in spinal dorsal horn in rats. METHDOS: Measurement of pain intensity rating (PIR), NADPH-d histochemistry, and Fos immunohistochemistry were adopted. CONCLUSION: Cor inhibits formalin-induced Hyperalgesia by the decrease of NOS-positive neurons in The spinal dorsal horn of rats.

机译：目的：研究促肾上腺皮质激素（Cor）对福尔马林诱导的大鼠痛觉过敏和脊髓背角一氧化氮合酶（NOS）阳性神经元变化的影响。 METHDOS：采用疼痛强度等级（PIR），NADPH-d组织化学和Fos免疫组织化学的测量方法。结论：Cor通过减少大鼠脊髓背角NOS阳性神经元抑制福尔马林诱导的痛觉过敏。

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《Acta Pharmacologica Sinica》 |1999年第8期|p.737-740|共4页
作者
Zhou Hong-Jie; Li Hai-Di; Li Xi-Cheng;
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正文语种 eng
中图分类药理学;
关键词
corticotropin; nitric-oxide synthase; spinal cord;

机译：促肾上腺皮质激素一氧化氮合酶脊髓;

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1. Increased formalin-induced pain and expression of fos neurons in the lumbar spinal cord of prenatally stressed infant rats. [J] . Butkevich IP, Barr GA, Mikhailenko VA, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2006,第3期

机译：福尔马林引起的疼痛和产前应激的幼鼠腰脊髓中fos神经元的表达增加。
2. Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception. [J] . Anderson LE, Seybold VS Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2000,第1期

机译：磷酸化的cAMP反应元件结合蛋白在福尔马林诱导的伤害感受中的大鼠脊髓神经激肽-1受体免疫反应性神经元中增加。
3. Oxysophoridine through intrathecal injection induces antinociception and increases the expression of the GABAA α 1 Receptor in the spinal cord of mice [J] . YangG., GaoJ., JiaY., Planta medica: Natural products and medicinal plant research . 2012,第9期

机译：鞘内注射氧代槐定碱可诱导镇痛作用并增加小鼠脊髓中GABAAα1受体的表达
4. Effects of chronic intrathecal infusion of BDNF on interneuronal activity in a large animal model of spinal cord injury [C] . F. Marchionne, A. J. Krupka, M. A. Lemay IEEE Signal Processing in Medicine and Biology Symposium . 2017

机译：慢性鞘内注射BDNF对大型脊髓损伤动物模型中神经元间活性的影响
5. Intrathecal Delivery of BDNF to the Lumbar Spinal Cord via Implanted Mini-Pump Restores Stepping and Modulates the Activity of the Lumbar Spinal Interneurons in a Large Animal Model of Spinal Cord Injury [D] . Marchionne, Francesca. 2017

机译：BDNF鞘内植入微型泵向腰脊髓鞘内递送恢复步进，并调节大型脊髓损伤动物模型中的腰椎间神经元的活性。
6. Phosphorylation of Transcription Factor CREB in Rat Spinal Cord after Formalin-Induced Hyperalgesia: Relationship toc-fos Induction [O] . Ru-Rong Ji, Fabio Rupp 1997

机译：福尔马林诱导痛觉过敏后大鼠脊髓中转录因子CREB的磷酸化：与toc-fos诱导的关系
7. Phosphorylation of Transcription Factor CREB in Rat Spinal Cord after Formalin-Induced Hyperalgesia: Relationship toc-fosInduction [O] . Ru-Rong Ji, Fabio Rupp 1997

机译：福尔马林诱导的痛觉过敏症后大鼠脊髓转录因子Creb的磷酸化：关系到培制 - 培制

Intrathecal injection of corticotropin inhibited nitric-oxide synthase-positive neuron increase in rat spinal cord after formalin-induced hyperalgesia

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