Schizontocidal effects of oral artesrunate on Plasmodium berghei in mice and P knowlesi in monkeys

Shi Yun-Lin; Li Guo-Fu; Zhao Jing-Hua

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Schizontocidal effects of oral artesrunate on Plasmodium berghei in mice and P knowlesi in monkeys

机译：口服青蒿琥酯对小鼠柏氏疟原虫和猴子P Knowlesi的杀螨作用

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AIM: To study the blood schizontocidal effect of oral artesunate on P berghei in mice and P knowlesi in monkey. METHODS: Effects of artesunate and chloroquine were detected with "4-day test" on P knowlesi in Macaca mudatta. CONCLUSION: The study of effects of oral artesunate in P Berghei/mice and P knwolesi/Macaca mulatta model Provided a sueful index for clinical trial.

机译：目的：研究口服青蒿琥酯对小鼠伯氏疟原虫和猴磷诺氏菌的血吸虫杀伤作用。方法：采用“ 4天试验”检测了猕猴泥P中的青蒿琥酯和氯喹的影响。结论：口服青蒿琥酯对P Berghei /小鼠和P knwolesi / Macaca mulatta模型影响的研究为临床试验提供了可靠的指标。

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来源
《Acta Pharmacologica Sinica》 |1999年第8期|p.755-758|共4页
作者
Shi Yun-Lin; Li Guo-Fu; Zhao Jing-Hua;
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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
artesunate; chloroquine; Plasmodium berghei;

机译：青蒿琥酯氯喹伯氏疟原虫;

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Schizontocidal effects of oral artesrunate on Plasmodium berghei in mice and P knowlesi in monkeys

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