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Platelet activating factor-induced P-selection expression in platelets and its related signal transduction

机译:血小板活化因子诱导的血小板P选择表达及其相关信号转导

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摘要

AIM: To study the intracellular signal transduction mechanisms of platelet activating factor (PAF)-induced platelet P-selectin expression. METHODS: Human bolld platelets were used to test the effect of PAF- induced P-selectin expression using flow cytometry. CONCLUSION: Multiple signal transduction Pathways, including protein typrosine phsophorylation Na~+/H~+ exchange, and Ca~2+ mobilization, mediated PAF-induced P-selectin expression.
机译:目的:研究血小板活化因子(PAF)诱导的血小板P-选择素表达的细胞内信号转导机制。方法:采用人bolt血小板流式细胞术检测PAF诱导的P-选择素表达的影响。结论:多种信号转导途径包括蛋白酪氨酸磷酸化Na〜+ / H〜+交换和Ca〜2 +动员,介导PAF诱导的P-选择素表达。

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