Effects of agmatine on afterdepolarizations induced by isopro- terenol in guinea pig papillary muscles

Li Xiao-Tao; He Rui-Rong

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Effects of agmatine on afterdepolarizations induced by isopro- terenol in guinea pig papillary muscles

机译：胍丁胺对异丙肾上腺素引起的豚鼠乳头肌后去极化的影响

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AIM: To study the effects of agmatine (Agm) on early afterdepolarizations (EAD) and delayed afterdepolarizations (DAD) induced by isoproterenol (Iso) in guinea pig papillary muscles. METHODS: EAD and DAD were recorded using intracellular glass Microelectrode technique. CONCLUTION: The inhibitory effects of Agm on EAD and DAD induced by Iso in papillary Muscles is related to the reduction in calcium influx and Mediated by α_2-AR and/or IR.

机译：目的：研究胍丁胺（Agm）对豚鼠乳头肌异丙肾上腺素（Iso）引起的早期除极后（EAD）和延迟除极后（DAD）的影响。方法：采用细胞内玻璃微电极技术记录EAD和DAD。结论：Agm对Iso诱导的乳头肌EAD和DAD的抑制作用与α_2-AR和/或IR介导的钙内流减少有关。

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《Acta Pharmacologica Sinica》 |1999年第11期|p.1039-1042|共4页
作者
Li Xiao-Tao; He Rui-Rong;
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正文语种 eng
中图分类药理学;
关键词
agmatine; papillary muscles; electrophysiology;

机译：胍丁胺乳头肌电生理;

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专利

1. EARLY AFTERDEPOLARIZATIONS AND TRIGGERED ACTIVITY INDUCED BY ENDOTHELIN IN GUINEA PIG PAPILLARY MUSCLES [J] . ZHANG ZHAO, LI YC-LONG, HE RUI-RONG Chinese journal of physiological sciences . 1996,第2期

机译：内皮素在几内亚猪乳头肌中引起的早期去极化和触发活性
2. Mechanisms of Early Afterdepolarizations and Triggered Activity in Guinea Pig Papillary Muscles Induced by Histamine [J] . 无中国药学（英文版） . 1994,第002期

机译：组胺诱导豚鼠乳头肌早期除极化和触发活性的机制
3. Mechanisms of Early Afterdepolarizations and Triggered Activity in Guinea Pig Papillary Muscles Induced by Histamine [J] . WuX 中国药学：英文版 . 1994,第002期

机译：组胺诱导豚鼠乳头肌早期除极化和触发活性的机制
4. Structure Related Modification of the Shock Induced Excitation in Guinea Pig Papillary Muscle [C] . Windisch, H., Platzer, Engineering in Medicine and Biology Society, 2007 Annual International Conference of the IEEE . 2007

机译：豚鼠乳头肌电击诱发兴奋的结构相关修饰
5. Differing Spatial Features of Calcium Transients during Early and Delayed Afterdepolarizations in Guinea Pig Ventricular Myocytes [D] . 三浦昌人 1993

机译：豚鼠心室肌细胞早期和延迟去极化过程中钙瞬变的不同空间特征
6. Electrophysiological effects of CI-980 a tubulin binding agent on guinea-pig papillary muscles [O] . Onésima Pérez, Carmen Valenzuela, Eva Delpón, 1997

机译：微管蛋白结合剂CI-980对豚鼠乳头肌的电生理作用
7. Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle. [O] . W A Coetzee, L H Opie 1987

机译：缺血组分及代谢抑制对豚鼠乳头肌延迟后递血的影响。
8. Structure Related Membrane Polarizations in Field Stimulated Guinea Pig Papillary Muscle. [R] . Windisch, H., Dapra, D., Kohler, H., 2001

机译：野外刺激豚鼠乳头肌的结构相关膜极化。

Effects of agmatine on afterdepolarizations induced by isopro- terenol in guinea pig papillary muscles

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