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Empirical Evaluation of the Generalizability of the Sample from the Multimodal Treatment Study for ADHD

机译:多动症多模式治疗研究中样本可推广性的实证评估

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Randomized controlled trials (RCTs) are criticized for the questionable generalizability of their patient samples to real world populations. This study compared the demographic and clinical characteristics of children from the Multimodal Treatment Study of Children with ADHD (MTA) to those from the NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study and the National Health and Nutrition Examination Survey (NHANES). On the whole, we found no compelling evidence against the representativeness of the MTA sample, but the limited power from MECA and NHANES may have lead to noteworthy differences between datasets being statistically nonsignificant.
机译:人们批评随机对照试验(RCT)的患者样本对现实世界人群的可概括性。这项研究比较了多动症儿童多模式治疗研究(MTA)和NIMH儿童和青少年精神障碍流行病学方法(MECA)研究以及国家健康与营养调查(NIMH)的儿童的人口统计学和临床​​特征。 NHANES)。总体而言,我们没有发现有力的证据证明MTA样本具有代表性,但MECA和NHANES的功能有限可能导致数据集之间的显着差异在统计学上不显着。

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