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3D Printing and Nanotechnology: A Multiscale Alliance in Personalized Medicine

机译：3D印刷和纳米技术：个性化医学中的多尺度联盟

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摘要

3D printing and nanotechnology have been two important tools in the development of therapeutic approaches for personalized medicine. More recently, their alliance has been improved in an effort to build innovative, versatile, multifunctional, and/or smart medical and pharmaceutical products. Therefore, an extensive review about scientific studies that ally 3D printing and nanomaterials in the development of new approaches for pharmaceutical and medical applications for the treatment and prevention of diseases is presented here. The articles are classified into five categories according to their main application: Cell growth and tissue engineering, antimicrobial, drug delivery, stimulus-response, and theranostics. Semisolid extrusion, inorganic nanoparticles, and cell growth and tissue engineering are the most reported 3D printing technique, type of nanomaterial, and application, respectively. The increase in papers dedicated to these areas is also notable, especially in the 2019 and 2020, when semisolid extrusion became the most used technique, overcoming fused deposition modelling. In fact, this review highlights that the possibility of an alliance between 3D printing and nanotechnology for the production of multiscale materials is undoubtedly a great opportunity for knowledge and innovation in the pharmaceutical and medical area.
机译：3D印刷和纳米技术已经有两个重要的工具，用于展开个性化医学的治疗方法。最近，他们的联盟在努力中得到了改进，以建立创新，多功能，多功能和/或智能医疗和药品。因此，这里介绍了关于亚利3D印刷和纳米材料在此处介绍了用于治疗和预防疾病的新方法的科学研究的科学研究的广泛综述。文章根据其主要应用分为五类：细胞生长和组织工程，抗微生物，药物递送，刺激反应和治疗剂。半固体挤出，无机纳米粒子和细胞生长和组织工程分别是据报道的3D印刷技术，纳米材料类型和应用。致力于这些区域的论文的增加也是值得注意的，特别是在2019年和2020年，当半固体挤出成为最常用的技术时，克服融合沉积建模。事实上，这篇综述凸显了3D印刷和纳米技术在生产多尺度材料的纳米技术之间的可能性无疑是制药和医疗区知识和创新的绝佳机会。

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  • 来源
    《Advanced Functional Materials》 |2021年第16期|2009691.1-2009691.35|共35页
  • 作者

    dos Santos Juliana; de Oliveira Rafaela S.; de Oliveira Thayse V; Velho Maiara C.; Konrad Martina V; da Silva Guilherme S.; Deon Monique; Beck Ruy C. R.;

  • 作者单位

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Dept Prod & Controle Medicamentos Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Dept Prod & Controle Medicamentos Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

    Univ Fed Rio Grande do Sul Programa Posgrad Ciencias Farmaceut Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil|Univ Fed Rio Grande do Sul Dept Prod & Controle Medicamentos Ave Ipiranga 2752 BR-90610000 Porto Alegre RS Brazil;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    additive manufacturing; biomedical; drug; fused deposition modelling; nanoparticle; semisolid extrusion;

    机译：添加剂制造;生物医学;药物;融合沉积建模;纳米粒子;半固体挤压;

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