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Strain-Isolating Materials and Interfacial Physics for Soft Wearable Bioelectronics and Wireless, Motion Artifact-Controlled Health Monitoring

机译:柔性耐磨生物电体和无线,运动伪影控制健康监测的应变隔离材料和界面物理

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摘要

Recent developments of micro-sensors and flexible electronics allow for the manufacturing of health monitoring devices, including electrocardiogram (ECG) detection systems for inpatient monitoring and ambulatory health diagnosis, by mounting the device on the chest. Although some commercial devices in reported articles show examples of a portable recording of ECG, they lose valuable data due to significant motion artifacts. Here, a new class of strain-isolating materials, hybrid interfacial physics, and soft material packaging for a strain-isolated, wearable soft bioelectronic system (SIS) is reported. The fundamental mechanism of sensor-embedded strain isolation is defined through a combination of analytical and computational studies and validated by dynamic experiments. Comprehensive research of hard-soft material integration and isolation mechanics provides critical design features to minimize motion artifacts that can occur during both mild and excessive daily activities. A wireless, fully integrated SIS that incorporates a breathable, perforated membrane can measure real-time, continuous physiological data, including high-quality ECG, heart rate, respiratory rate, and activities. In vivo demonstration with multiple subjects and simultaneous comparison with commercial devices captures the SIS's outstanding performance, offering real-world, continuous monitoring of the critical physiological signals with no data loss over eight consecutive hours in daily life, even with exaggerated body movements.
机译:微传感器和柔性电子产品的最新发展允许制造健康监测装置,包括用于在胸部上安装装置的用于住院监测和动态健康诊断的心电图(ECG)检测系统。虽然报告文章中的一些商业设备显示了ECG的便携式记录的示例,但由于显着的运动伪影,它们失去了有价值的数据。这里,据报道了一种新的应变隔离材料,混合界面物理和软材料包装用于菌株隔离,可穿戴软生物电解系统(SIS)。传感器嵌入式应变隔离的基本机制通过分析和计算研究的组合来定义,并通过动态实验验证。综合研究硬质材料集成和隔离力学提供了关键设计特征,以最大限度地减少温和和过度日常活动中可能发生的运动伪影。无线,完全集成的SIS,包括透气,穿孔膜可以测量实时,连续生理数据,包括高质量的心电图,心率,呼吸率和活动。在Vivo演示中,具有多个科目和与商业设备的同步比较捕获了SIS的出色性能,提供了现实世界,连续监测了日常生活连续八小时内没有数据损失的关键生理信号,即使有夸大的身体运动。

著录项

  • 来源
    《Advanced Functional Materials》 |2021年第36期|2104070.1-2104070.12|共12页
  • 作者单位

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA;

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA;

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA;

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA;

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA;

    Korea Adv Inst Sci & Technol Sch Elect Engn Daejeon 34141 South Korea;

    Georgia Inst Technol George W Woodruff Sch Mech Engn Ctr Human Centr Interfaces & Engn Inst Elect & Nanotechnol Atlanta GA 30332 USA|Georgia Inst Technol Wallace H Coulter Dept Biomed Engn Parker H Petit Inst Bioengn & Biosci Atlanta GA 30332 USA|Emory Univ Atlanta GA 30332 USA|Georgia Inst Technol Inst Robot & Intelligent Machines Flexible & Wearable Elect Adv Res Inst Mat Neural Engn Ctr Atlanta GA 30332 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    hybrid interfacial physics; motion artifact control; soft wearable bioelectronics; strain isolation;

    机译:混合界面物理;运动伪影控制;柔软的可穿戴生物电体化;应变隔离;

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