• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Advanced Functional Materials >3D Printing of Bioinspired Alginate-Albumin Based Instant Gel Ink with Electroconductivity and Its Expansion to Direct Four-Axis Printing of Hollow Porous Tubular Constructs without Supporting Materials
【24h】

3D Printing of Bioinspired Alginate-Albumin Based Instant Gel Ink with Electroconductivity and Its Expansion to Direct Four-Axis Printing of Hollow Porous Tubular Constructs without Supporting Materials

机译：基于生物悬浮的藻酸盐 - 白蛋白基于凝胶墨水的3D印染导电性及其膨胀，以指示中空多孔管状构建体的四轴印刷而无支撑材料

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A successful 3D printable hydrogel ink needs not only biofunctionalities but also minimal fabrication steps such as multiple crosslinking sites, high printability, cytocompatibility, high shape fidelity, stability, shear thinning, robust properties, and less time-consuming processing steps, by maximizing known material chemistries and functionalities. This work reports a novel bioinspired conjugate with polysaccharide (alginate)-tannic acid (TA)-protein (bovine serum albumin) to fabricate proteoglycan-like gels, which are 3D printable with multilayers, shear-thinning, elastic, electroconductive (with carbon nanotubes), controlled crosslinking/degradation through multiple crosslinking mechanisms (TA, Ca2+ ions, and NaIO4 oxidation), and interactions with cytocompatible hydrogel system. The synthesis process is simple, and gelation (within 2 h) is ensured without any chemical crosslinking agents (at room temperature). While cell-adhesive albumin largely improves cytocompatibility, carbon nanotubes in the gel give electrical conductivity in the different four-axis 3D printed structures, including large hollow tubular constructs. This work demonstrates promising results of electroconductive proteoglycan-like gel ink to address the challenges in 3D/four-axis ink printing such as synthesis, printability, shape fidelity, electroconductivity, controlled fabrication and degradation, cytocompatibility, and multiple crosslinking abilities to maintain the dimensions of the diversely printed constructs.
机译：一个成功的三维可印刷的水凝胶油墨需要不仅biofunctionalities而且这样最小的制造步骤为多个交联点，高可印刷性，细胞相容性，高形状保真度，稳定性，剪切稀化，鲁棒性，和耗时更少的处理步骤，通过最大化公知的材料化学和功能。这项工作报告与多糖的新型仿生缀合物（海藻酸盐）-tannic酸（TA） - 蛋白质（牛血清白蛋白）来制造蛋白多糖样的凝胶，其是三维可印刷有多层，剪切稀化，弹性，导电性（与碳纳米管），通过多个交联机理（TA，Ca 2+离子，和高碘酸钠氧化），并用细胞相容性水凝胶系统的相互作用控制的交联/降解。合成工艺简单，和凝胶化（2小时内），确保没有任何化学交联剂（在室温下）。虽然细胞粘附性白蛋白很大程度上提高细胞相容性，碳纳米管在凝胶给在不同的四轴三维印刷结构的导电性，包括大型中空管状结构。这项工作表明的有希望的结果导电蛋白聚糖状凝胶墨水，以解决在3D /四轴油墨印刷，如合成，可印刷性，形状的保真度，导电性，控制制造和降解，细胞相容性，和多个交联的能力，以维持尺寸的挑战的不同地印刷构建体。

著录项

  • 来源
    《Advanced Functional Materials》 |2021年第45期|2104441.1-2104441.13|共13页
  • 作者

    Janarthanan Gopinathan; Lee Sumin; Noh Insup;

  • 作者单位

    Seoul Natl Univ Sci & Technol Dept Chem & Biomol Engn Seoul 01811 South Korea|Seoul Natl Univ Sci & Technol Convergence Inst Biomed Engn & Biomat Seoul 01811 South Korea;

    Seoul Natl Univ Sci & Technol Dept Chem & Biomol Engn Seoul 01811 South Korea;

    Seoul Natl Univ Sci & Technol Dept Chem & Biomol Engn Seoul 01811 South Korea|Seoul Natl Univ Sci & Technol Convergence Inst Biomed Engn & Biomat Seoul 01811 South Korea;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    alginate; biomaterial inks; bovine serum albumin; four-axis printing; tannic acid;

    机译：藻酸盐;生物材料油墨;牛血清白蛋白;四轴印刷;单宁酸;

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号