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Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

机译：用于个性化和预防医学的可穿戴微型传感器技术

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摘要

The unprecedented medical achievements of the last century have dramatically improved our quality of life. Today, the high cost of many healthcare approaches challenges their long-term financial sustainability and translation to a global scale. The convergence of wearable electronics, miniaturized sensor technologies, and big data analysis provides novel opportunities to improve the quality of healthcare while decreasing costs by the very early stage detection and prevention of fatal and chronic diseases. Here, some exciting achievements, emerging technologies, and standing challenges for the development of non-invasive personalized and preventive medicine devices are discussed. The engineering of wire-and power-less ultra-thin sensors on wearable biocompatible materials that can be placed on the skin, pupil, and teeth is reviewed, focusing on common solutions and current limitations. The integration and development of sophisticated sensing nano-materials are presented with respect to their performance, showing exemplary implementations for the detection of ultra-low concentrations of biomarkers in complex mixtures such as the human sweat and breath. This review is concluded by summarizing achievements and standing challenges with the aim to provide directions for future research in miniaturized medical sensor technologies.
机译：上个世纪前所未有的医学成就极大地改善了我们的生活质量。如今，许多医疗保健方法的高成本挑战了它们的长期财务可持续性以及向全球范围的转化。可穿戴电子设备，小型传感器技术和大数据分析的融合为通过早期发现和预防致命和慢性疾病而降低医疗费用提供了改善医疗保健质量的新机会。在此，讨论了无创个性化和预防医学设备开发的一些令人兴奋的成就，新兴技术和面临的挑战。对可放在皮肤，瞳孔和牙齿上的可穿戴生物兼容材料上的无电线和无电源超薄传感器的工程进行了审查，重点是常见的解决方案和电流限制。介绍了先进传感纳米材料的性能集成和开发情况，展示了用于检测人类汗水和呼吸等复杂混合物中超低浓度生物标志物的示例性实现。本综述通过总结成就和面临的挑战来结束，旨在为小型化医学传感器技术的未来研究提供方向。

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  • 来源
    《Advanced Functional Materials》 |2017年第15期|1605271.1-1605271.19|共19页
  • 作者

    Tricoli Antonio; Nasiri Noushin; De Sayan;

  • 作者单位

    Australian Natl Univ, Res Sch Engn, Nanotechnol Res Lab, Canberra, ACT 2601, Australia;

    Australian Natl Univ, Res Sch Engn, Nanotechnol Res Lab, Canberra, ACT 2601, Australia;

    Australian Natl Univ, Res Sch Engn, Nanotechnol Res Lab, Canberra, ACT 2601, Australia;

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