• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Advanced Functional Materials >Engineering Iron Oxide Hollow Nanospheres to Enhance Antimicrobial Property: Understanding the Cytotoxic Origin in Organic Rich Environment
【24h】

Engineering Iron Oxide Hollow Nanospheres to Enhance Antimicrobial Property: Understanding the Cytotoxic Origin in Organic Rich Environment

机译：工程氧化铁空心纳米球，以增强抗菌性能：了解有机丰富环境中的细胞毒起源。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Engineered magnetic iron oxide nanoparticles with surprisingly high antimicrobial activity and excellent safety profiles to mammalian cell lines have been developed. Hematite hollow nanospheres (HNSs) are prepared by a facile hard templating method; reduction of hematite HNSs by H-2 leads to magnetite HNSs. The antimicrobial activity of magnetite HNSs towards Gram negative (Escherichia coli) and Gram positive (Staphylococcus epidermidis) bacteria is evaluated against hematite HNSs and conventional magnetite (C-magnetite; diameter <50 nm). Superior antibacterial performance is observed for magnetite HNSs towards both E. coli and S. epidermidis over hematite HNSs and C-magnetite. The origin of the antimicrobial activity of magnetite HNSs is the high leaching of iron ions in the presence of microorganisms, which leads to high generation of reactive oxygen species. Magnetite HNSs allow multiple-fold increase in the generation of soluble iron ions over hematite HNSs and C-magnetite, showing that control over both the composition and nano structure is crucial to tune the antimicrobial activity of iron oxides. Based on the current findings, magnetic HNSs show promising potential antimicrobial applications.
机译：已开发出具有令人惊讶的高抗菌活性和对哺乳动物细胞系极好的安全性的工程磁性氧化铁纳米粒子。赤铁矿空心纳米球（HNSs）是通过一种简便的硬模板法制备的。 H-2对赤铁矿HNS的还原会导致磁铁矿HNS。评估了磁铁矿HNS对革兰氏阴性（Escherichia coli）和革兰氏阳性（Staphylococcus epidermidis）细菌的抗微生物活性，针对赤铁矿HNSs和常规磁铁矿（C-磁铁矿；直径<50 nm）。观察到磁铁矿HNS对大肠杆菌和表皮葡萄球菌的抗菌性能均优于赤铁矿HNS和C-磁铁矿。磁铁矿HNS的抗菌活性的起源是在微生物存在下铁离子的高浸出，这导致高活性氧的产生。磁铁矿HNS允许可溶性铁离子的生成比赤铁矿HNS和C-磁铁矿成倍增加，这表明控制组成和纳米结构对于调节氧化铁的抗菌活性至关重要。根据目前的发现，磁性HNS具有潜在的抗菌应用前景。

著录项

  • 来源
    《Advanced Functional Materials》 |2016年第30期|5408-5418|共11页
  • 作者

    Nor Yusilawati Ahmad; Zhou Liang; Meka Anand Kumar; Xu Chun; Niu Yuting; Zhang Hongwei; Mitter Neena; Mahony Donna; Yu Chengzhong;

  • 作者单位

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

    Univ Queensland, Queensland Alliance Agr & Food Innovat, Brisbane, Qld 4072, Australia;

    Univ Queensland, Queensland Alliance Agr & Food Innovat, Brisbane, Qld 4072, Australia;

    Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号