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Acoustic Nanofluidics via Room-Temperature Lithium Niobate Bonding: A Platform for Actuation and Manipulation of Nanoconfined Fluids and Particles

机译:通过室温铌酸锂键合的声纳米流体:纳米约束流体和颗粒的驱动和操纵的平台。

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摘要

Controlled nanoscale manipulation of fluids and colloids is made exceptionally difficult by the dominance of surface and viscous forces. Acoustic waves have recently been found to overcome similar problems in microfluidics, but their ability to do so at the nanoscale remains curiously unexplored. Here, it is shown that 20 MHz surface acoustic waves (SAW) can manipulate fluids, fluid droplets, and particles, and drive irregular and chaotic fluid flow within fully transparent, high-aspect ratio 50-250 nm tall nanoslits fabricated via a new direct, room temperature bonding method for lithium niobate (LN). Applied in the same direction, SAW increases the capillary filling rate of the hydrophilic LN nanoslit by 2-5 times. Applied in opposition, the SAW switches the flow direction and drains the channel against 1 MPa capillary pressure, and can be used to controllably manipulate approximate to 10 fL droplets. Finally, entire 10 mu L droplets can be sieved via SAW through the nanoslit to pass only particles smaller than its height, providing pumpless size exclusion separation.
机译:由于表面力和粘性力的支配性,使流体和胶体的可控纳米级处理异常困难。最近发现声波克服了微流体学中的类似问题,但奇怪的是,它们在纳米级的能力还没有得到探索。此处显示了20 MHz的表面声波(SAW)可以操纵流体,液滴和粒子,并通过完全透明,高纵横比的50-250 nm高纳米缝隙驱动不规则和混沌的流体流,这些缝隙是通过新的直接波导管制造的,室温粘结铌酸锂(LN)的方法。在相同方向上应用SAW,可使亲水性LN纳米缝的毛细管填充率提高2-5倍。相反地​​,SAW可以切换流向,并在1 MPa的毛细管压力下排空通道,可用于可控地操纵大约10 fL的液滴。最后,整个10μL的液滴可以通过SAW筛分通过纳米缝,仅通过小于其高度的颗粒,从而实现了无泵尺寸排阻分离。

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  • 来源
    《Advanced Functional Materials》 |2016年第43期|7861-7872|共12页
  • 作者单位

    Univ Calif San Diego, Dept Mech & Aerosp Engn, Med Adv Devices Lab, Ctr Med Devices & Instrumentat, 9500 Gilman Dr, La Jolla, CA 92093 USA;

    Univ Calif San Diego, Dept Mech & Aerosp Engn, Med Adv Devices Lab, Ctr Med Devices & Instrumentat, 9500 Gilman Dr, La Jolla, CA 92093 USA;

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