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Enzyme-Based Nanoscale Composites for Use as Active Decontamination Surfaces

机译：基于酶的纳米复合材料，用作活性去污表面

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摘要

Perhydrolase S54V (AcT) effectively catalyzes the perhydrolysis of propylene glycol diacetate (PCD) to generate peracetic acid (PAA). PAA is a potent oxidant used for sanitization and disinfection, with broad effectiveness against bacteria, yeasts, fungi, and spores. In this study, active and stable composites are developed by incorporating AcT-carbon nanotube conjugates into polymer and latex-based paint. At a conjugate loading of 0.16% (w/v), the composite generated 11 him PAA in 20 min, capable of killing more than 99% spores initially charged at 10~6 colony-forming units per milliliter.
机译：过水解酶S54V（AcT）有效催化丙二醇二乙酸酯（PCD）的过水解，生成过乙酸（PAA）。 PAA是用于消毒和消毒的有效氧化剂，对细菌，酵母，真菌和孢子具有广泛的效力。在这项研究中，通过将AcT-碳纳米管共轭物掺入聚合物和乳胶基涂料中来开发活性和稳定的复合材料。在共轭负载量为0.16％（w / v）的情况下，复合物在20分钟内产生11他的PAA，能够杀死最初以每毫升10〜6个菌落形成单位加入的99％以上的孢子。

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  • 来源
    《Advanced Functional Materials》 |2010年第3期|392-398|共7页
  • 作者

    Cerasela Zoica Dinu; Guangyu Zhu; Shyam Sundhar Bale; Gaurav Anand; Philippa J.Reeder; Karl Sanford; Gregg Whited; Ravi S. Kane; Jonathan S. Dordick;

  • 作者单位

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Cenencor International Palo Alto, CA 94304 (USA);

    Cenencor International Palo Alto, CA 94304 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

    Department of Chemical and Biological Engineering Rensselaer Nanotechnology Center and Center for Biotechnology & Interdisciplinary Studies Rensselaer Polytechnic Institute Troy, NY 12180 (USA);

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