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Thermochemical Nanolithography of Multifunctional Nanotemplates for Assembling Nano-Objects

机译：多功能纳米模板用于组装纳米物体的热化学纳米光刻。

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摘要

Nanoscale chemical patterning of different chemical species (amine, fhiol, aldehyde, and biotin) in independent nanopatterns is achieved by the iterative application of thermochemical nanolithography (TCNL) to inscribe amine patterns followed by their chemical conversion to other functional groups. Due to the unique chemical stability of the patterns, the resultant substrates can be stored for weeks and subsequently be used for covalent and molecular-recognition-based attachment of nano-objects using standard chemical protocols. In particular, the ability of this method to attach proteins and DNA to the chemical nanopatterns and to create co-patterns of two distinctive bioactive proteins is demonstrated.
机译：通过迭代应用热化学纳米光刻（TCNL）来刻画胺图案，然后将其化学转化为其他官能团，可以在独立的纳米图案中实现不同化学物种（胺，氟酚，醛和生物素）的纳米级化学图案化。由于图案具有独特的化学稳定性，因此可以使用标准化学方案将所得基质存储数周，然后用于基于共价和分子识别的纳米物体附着。特别地，证明了这种方法将蛋白质和DNA附着到化学纳米图案上并创建两个独特的生物活性蛋白质的共同图案的能力。

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  • 来源
    《Advanced Functional Materials》 |2009年第23期|3696-3702|共7页
  • 作者

    Debin Wang; Vamsi K. Kodali; William D. Underwood II; Jonas E. Jarvholm; Takashi Okada; Simon C. Jones; Mariacristina Rumi; Zhenting Dai; William P. King; Seth R. Marder; Jennifer E. Curtis; Elisa Riedo;

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    School of Physics and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    Department of New Materials and Biosystems Max-Planck-lnstitute for Metals Research Heisenbergstrasse 3, 70569 Stuttgart (Germany) Department of Biophysical Chemistry, University of Heidelberg INF 253, 69120 Heidelberg (Germany);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    Department of Mechanical Science and Engineering University of Illinois Urbana-Champaign Urbana, IL 61801 (USA);

    Department of Mechanical Science and Engineering University of Illinois Urbana-Champaign Urbana, IL 61801 (USA);

    School of Chemistry and Biochemistry and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Physics and Petit Institute for Bioengineering and Bioscience Georgia Institute of Technology Atlanta, GA 30332 (USA);

    School of Physics and Center for Organic Photonics and Electronics Georgia Institute of Technology Atlanta, GA 30332 (USA);

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