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A novel route to thermosensitive polymeric core-shell aggregates and hollow spheres in aqueous media

机译:在水介质中获得热敏聚合物核-壳聚集体和空心球的新途径

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摘要

Poly(epsilon-caprolactone)/poly(N-isopropylacrylamide) (PCL/PNIPAM) core-shell particles are obtained by localizing the polymerization of NIPAM and crosslinker methylene bisacrylamide around the surface of PCL nanoparticles. The resultant particles are converted to hollow PNIPAM spheres by simply degrading the PCL core with an enzyme. The hollow spheres are thermosensitive and display a reversible swelling and de-swelling at similar to 32 degrees C.
机译:聚(ε-己内酯)/聚(N-异丙基丙烯酰胺)(PCL / PNIPAM)核-壳颗粒是通过将NIPAM和交联剂亚甲基双丙烯酰胺在PCL纳米颗粒表面附近局部化而获得的。通过简单地用酶降解PCL核,将所得颗粒转化为空心PNIPAM球。中空球是热敏性的,并且在类似于32摄氏度的温度下显示可逆的溶胀和消肿。

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