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首页> 外文期刊>Advanced Materials >Chitosan-Based Inverse Opals: Three-Dimensional Scaffolds with Uniform Pore Structures for Cell Culture
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Chitosan-Based Inverse Opals: Three-Dimensional Scaffolds with Uniform Pore Structures for Cell Culture

机译：基于壳聚糖的反蛋白石：具有均匀孔结构用于细胞培养的三维支架。

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摘要

Tissue engineering is a promising approach to the development of biological substitutes that regenerate, replace, maintain, or improve the function of damaged tissues. Among various topics related to tissue engineering, the structures and properties of the scaffolds have been studied extensively in the context of material science and biomedical engineering. There are a number of generic requirements for the scaffold: 1) the material used for fabricating the scaffold must be biocompatible and biodegradable, together with positive responses from the seeded cells; 2) the scaffold should contain a network of pores, and favorably in the form of 3D interconnected architecture; and 3) the scaffold should have proper mechanical properties to suit the specific applications, including the generation of cartilage, bone, artificial blood vessel, among others.
机译：组织工程学是开发可再生，替代，维持或改善受损组织功能的生物替代物的有前途的方法。在与组织工程有关的各种主题中，在材料科学和生物医学工程的背景下，对支架的结构和性质进行了广泛的研究。支架有许多通用要求：1）用于制造支架的材料必须具有生物相容性和可生物降解性，并需要接种细胞的积极响应； 2）支架应包含孔网，并且最好采用3D互连架构的形式； 3）脚手架应具有适合特定应用的适当机械性能，包括软骨，骨骼，人造血管等的生成。

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  • 来源
    《Advanced Materials》 |2009年第29期|2997-3001|共5页
  • 作者

    Sung-Wook Choi; Jingwei Xie; Younan Xia;

  • 作者单位

    Department of Biomedical Engineering, Washington University St. Louis, MO 63130 (USA);

    Department of Biomedical Engineering, Washington University St. Louis, MO 63130 (USA);

    Department of Biomedical Engineering, Washington University St. Louis, MO 63130 (USA);

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