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首页> 外文期刊>Advanced Materials >Domino Reaction Encoded Heterogeneous Colloidal Microswarm with On-Demand Morphological Adaptability
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Domino Reaction Encoded Heterogeneous Colloidal Microswarm with On-Demand Morphological Adaptability

机译:Domino反应编码异质胶体微水,随需按需形态适应性

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摘要

Emulating natural swarm intelligence with group-level functionality in artificial micro/nanorobotic systems offers an opportunity to sublimate the limited functions of individuals and revolutionize their applications. However, achieving synchronous operation of microswarms with environmental adaptability and cooperative tasking capability remains a challenge. Here, an adaptive and heterogeneous colloidal magnetic microswarm with domino reaction encoded cooperative functions is presented. Through programming external magnetic fields, the system self-organizes into two swarm states, that is, vortex and ribbon microswarms, which can switch between each other reversibly within seconds, allowing to traverse tortuous, branched, and confined environments through adaptive morphological transformation. By specializing subgroups of building blocks with separate functions, cooperative tasking capability is integrated into the heterogeneous system following a "division of labor" manner. Given targeted therapy as a proof-of-concept task, the coordinated delivery of heterogeneous colloidal system across a complex environment with an access rate higher than 90% is demonstrated, and the specialization and cooperation between building blocks to disrupt multiple growth pathways of cancer cells via domino reaction are realized. The reconfigurable microswarm with hierarchical functionality presents a bioinspired approach to adapt to environmental variations and address multitasking requirements, which advances the development of microrobotic swarms and promises major benefits in biomedical fields.
机译:用人造微/纳米毒素系统中与组级功能模拟自然群智能,提供了升华个人有限功能的机会,并彻底改变其应用。然而,实现了与环境适应性和合作任务能力的同步操作仍然是一个挑战。这里,提出了一种具有Domino反应编码的协作功能的自适应和异质胶体磁性微水。通过编程外部磁场,系统将自组织成两种群状态,即涡旋和带状微磁炉,可以通过适应性形态转换来逆转时秒的互相切换。通过专用具有单独功能的构建块的子组,合作任务能力在“分工”方式之后纳入异构体系。给予针对性的治疗作为概念验证任务,证明了高于90%的复杂环境的复杂环境的异质胶体系统的协调递送,以及建筑块之间的专业化和合作,破坏癌细胞的多种生长途径通过Domino反应实现。具有分层功能的可重新配置的微水展示了一种生物透明的方法,可以适应环境变化和地址多任务要求,这导致微生物群的发展,并承诺在生物医学领域的主要益处。

著录项

  • 来源
    《Advanced Materials》 |2021年第37期|2100070.1-2100070.13|共13页
  • 作者单位

    Chinese Univ Hong Kong Dept Mech & Automat Engn Shatin Hong Kong 999077 Peoples R China;

    Chinese Univ Hong Kong Dept Biomed Engn Shatin Hong Kong 999077 Peoples R China;

    Chinese Univ Hong Kong Dept Biomed Engn Shatin Hong Kong 999077 Peoples R China;

    Chinese Univ Hong Kong Dept Mech & Automat Engn Shatin Hong Kong 999077 Peoples R China;

    Chinese Univ Hong Kong Dept Mech & Automat Engn Shatin Hong Kong 999077 Peoples R China;

    Chinese Univ Hong Kong Dept Mech & Automat Engn Shatin Hong Kong 999077 Peoples R China|Chinese Univ Hong Kong Dept Biomed Engn Shatin Hong Kong 999077 Peoples R China|Chinese Univ Hong Kong Chow Yuk Ho Technol Ctr Innovat Med Shatin Hong Kong 999077 Peoples R China|Chinese Univ Hong Kong T Stone Robot Inst Shatin Hong Kong 999077 Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    adaptive transformation; colloidal microswarms; domino reaction; heterogeneous systems; intelligent micro; nanorobots; targeted delivery;

    机译:自适应转化;胶体微观武器;Domino反应;异构系统;智能微型;纳米虫;有针对性的交付;

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