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Hydrogels in biology and medicine: From molecular principles to bionanotechnology

机译:生物学和医学中的水凝胶:从分子原理到生物纳米技术

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摘要

Hydrophilic polymers are the center of research emphasis in nanotechnology because of their perceived "intelligence". They can be used as thin films, scaffolds, or nanoparticles in a wide range of biomedical and biological applications. Here we highlight recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for these applications. Natural, biohybrid, and synthetic hydrophilic polymers and hydrogels are analyzed and their thermodynamic responses are discussed. In addition, examples of the use of hydrogels for various therapeutic applications are given. We show how such systems' intelligent behavior can be used in sensors, microarrays, and imaging. Finally, we outline challenges for the future in intergrating hydrogels into biomedical applications.
机译:亲水聚合物因其“智能”而成为纳米技术研究的重点。它们可以在广泛的生物医学和生物学应用中用作薄膜,支架或纳米颗粒。在这里,我们重点介绍了针对这些应用工程化未交联和交联的亲水性聚合物的最新进展。分析了天然,生物杂化和合成亲水性聚合物和水凝胶,并讨论了它们的热力学响应。另外,给出了水凝胶用于各种治疗应用的实例。我们展示了如何在传感器,微阵列和成像中使用此类系统的智能行为。最后,我们概述了将水凝胶整合到生物医学应用中的未来挑战。

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