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Simple and Low-Cost Plasmonic Fiber-Optic Probe as SERS and Biosensing Platform

机译：简单且低成本的等离子等离子体光纤探针作为SERS和生物传感平台

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摘要

As an emerging and promising paradigm of nanophotonic "lab-on-a-chip" devices, plasmonic fiber-optic (FO) probes with nanopatterns suffer from high cost and a complex fabrication process, which keep them from becoming the preferred choice for most optical fiber sensing applications. In this paper, a nanopatterned FO probe is demonstrated to be a surface-enhanced Raman spectroscopy substrate and a plasmonic biosensor through theoretical simulations and experiments. The probe is assembled with imprinted nanocavities on the tip of the optical fiber and fabricated through a low-cost and facile method. The FO probe overcomes the shortcomings of conventional optical fiber sensors that have nanoscale patterns and structures, such as requiring a complex and time-consuming procedure, expensive specialized instruments, and experienced professional operation. Through investigating its surface sensitivity and the plasmonic coupling effect between Au nanoparticles and the nanocavity, this probe is found to have practical applications in the detection of biochemical molecules. The proposed FO probe can be produced under common experimental conditions, and its operation is simple and understandable, which serves as a new strategy for fabricating nanostructures on fiber tips.
机译：作为纳米光子“片上实验室”设备的新兴和有希望的范例，具有纳米图案的等离激元光纤（FO）探针成本高昂且制造工艺复杂，这使其无法成为大多数光学仪器的首选。光纤传感应用。本文通过理论模拟和实验证明了纳米图案的FO探针是表面增强的拉曼光谱衬底和等离子体生物传感器。该探针在光纤尖端组装有压印的纳米腔，并通过低成本，简便的方法进行制造。 FO探头克服了具有纳米级图案和结构的常规光纤传感器的缺点，例如要求复杂且耗时的过程，昂贵的专用仪器以及经验丰富的专业操作。通过研究其表面敏感性和金纳米颗粒与纳米腔之间的等离子体耦合效应，发现该探针在生化分子检测中具有实际应用。提出的FO探针可以在常见的实验条件下生产，并且其操作简单易懂，这是在纤维尖端上制造纳米结构的新策略。

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