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Cat (Fel d 1) and dog (Can f 1) allergen levels in cars, dwellings and schools

机译:汽车,住宅和学校中的猫(Fel d 1)和狗(Can f 1)过敏原水平

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Pets are an important source of indoor allergens. The aim of the study was to compare cat and dog allergen levels in cars, schools and homes. The study was carried out in 17 cars, 14 classrooms and 19 dwellings located in the highly industrialized and urbanized region of Poland. Dust and air samples were analyzed for Fel d 1 and Can f 1 using a double monoclonal ELISA assay. The highest amounts of cat and dog allergens (Fel d 1: 1169 mu g/g; Can f 1: 277 mu g/g) were found in dwellings with pets. Allergen concentrations were correlated with the number of animals kept at home. Although concentrations on automobile seats were lower, Fel d 1 levels exceeded 8 mu g/g in 23.5 % of cars and high levels of Can f 1 (> 10 mu g/g) were found in 17.6 % of cars. The study revealed that cars of pet owners may be reservoirs of cat and dog allergens even when animals are not transported in them. In schools, concentrations of pet allergens did not reach high levels, but the moderate levels of Fel d 1 (aeyen1-8 mu g/g) and Can f 1 (aeyen2-10 mu g/g) were detected in 42.9 and 7.1 % of the investigated classrooms. Concentrations of cat and dog allergen in schools were higher than in homes without pets. While airborne Fel d 1 and Can f 1 levels were found low, residential allergen concentrations in settled dust and air were correlated. The study results suggest that classrooms and cars of pet owners may be important sites of exposure to cat and dog allergens, though the highest concentrations of Fel d 1 and Can f 1 are found in homes of pet owners.
机译:宠物是室内过敏原的重要来源。该研究的目的是比较汽车,学校和家庭中猫和狗的过敏原水平。这项研究是在波兰高度工业化和城市化地区的17辆汽车,14个教室和19所住宅中进行的。使用双重单克隆ELISA分析法对灰尘和空气样品的Fel d 1和Can f 1进行了分析。猫和狗的过敏原含量最高(Fel d 1:1169 mu g / g; Can f 1:277 mu g / g)在有宠物的住宅中。过敏原浓度与饲养在家里的动物数量有关。尽管汽车座椅上的浓度较低,但Fel d 1含量在23.5%的汽车中超过8μg / g,而Can f 1(> 10μg / g)的高含量在17.6%的汽车中。研究表明,即使不携带动物,宠物主人的汽车也可能是猫和狗过敏原的储存库。在学校中,宠物过敏原的浓度没有达到很高的水平,但是检出的中等水平的Fel d 1(aeyen1-8μg / g)和Can f 1(aeyen2-10μg/ g)分别为42.9和7.1%被调查的教室。学校中猫和狗的过敏原浓度高于没有宠物的家庭。虽然发现空气中的Fel d 1和Can f 1水平较低,但沉降的粉尘和空气中的居民过敏原浓度却是相关的。研究结果表明,宠物主人的教室和汽车可能是暴露于猫和狗过敏原的重要场所,尽管在宠物主人家中发现的Fel d 1和Can f 1浓度最高。

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