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首页> 外文期刊>AIDS Research and Human Retroviruses >Short Communication: Molecular Characterization of HIV Type 1 BF Pol Recombinants from São Paulo, Brazil
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Short Communication: Molecular Characterization of HIV Type 1 BF Pol Recombinants from São Paulo, Brazil

机译:简短交流:来自巴西圣保罗的HIV 1型BF Pol重组子的分子表征

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摘要

In the Brazilian HIV-1 epidemic, subtypes B, C, and F1 are cocirculating in the population. Sequences of the partial pol gene from 463 HIV-1-infected patients were obtained from plasma samples and viral subtype was characterized. BF recombinants were found in 8% of the samples. Fifteen different patterns were observed. A CRF28_BF and CRF29_BF structure was found in 29.7% of the samples, CRF12_BF in 13.5%, and CRF39_BF in 2.7%. Two other patterns were identified in each of three samples. These findings could indicate a new CRF description, but to determine this a full length study is required.
机译:在巴西的HIV-1流行病中,B,C和F1亚型在人群中共同传播。从血浆样本中获得了463名HIV-1感染患者的部分pol基因序列,并对病毒亚型进行了表征。在8%的样品中发现了BF重组体。观察到十五种不同的模式。在29.7%的样本中发现了CRF28_BF和CRF29_BF的结构,在13.5%的样本中发现了CRF12_BF,在2.7%的样本中发现了CRF39_BF。在三个样本中的每个样本中还确定了另外两个模式。这些发现可能表明有新的CRF描述,但要确定这一点,需要进行全长研究。

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